Title:
SALT OF CURCUMIN MONOGLUCURONIDE
Document Type and Number:
WIPO Patent Application WO/2022/004873
Kind Code:
A1
Abstract:
The present invention provides: a derivative that is of curcumin monoglucuronide, that has excellent solubility and chemical stability, and that can be provided as a medicinal drug; and a method for producing said derivative. A salt that is of curcumin monoglucuronide and that is represented by formula (I) [in the formula, M represents a pharmaceutically acceptable cation], a hydrate thereof, or a solvate of any of those.
Inventors:
IMAIZUMI ATSUSHI (JP)
UMETA HITOMI (JP)
FUKUDA YASUMICHI (JP)
UMETA HITOMI (JP)
FUKUDA YASUMICHI (JP)
Application Number:
PCT/JP2021/025112
Publication Date:
January 06, 2022
Filing Date:
July 02, 2021
Export Citation:
Assignee:
THERABIOPHARMA INC (JP)
International Classes:
A61P3/06; A61K31/7034; A61P9/00; A61P25/28; A61P29/00; A61P35/00; A61P37/08; A61P39/06; C07H15/203
Domestic Patent References:
| WO2018003857A1 | 2018-01-04 |
Foreign References:
| JP2015054846A | 2015-03-23 |
Other References:
CAMILLE G. WERMUTH: "The Practice of Medicinal Chemistry", 31 August 1999, TEKUNOMIKKU , JP , ISBN: 4-924746-80-0, article BRADLEY D. ANDERSON; KARL P. FLORA: "34. Preparation of water-soluble organic compounds by salt formation: 34.1. Importance of water-soluble salts in the early stages of drug evaluation", pages: 347 - 348, XP009534278
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Download PDF: