Title:
SALT OF PYRAZOLE DERIVATIVE AND PREPARATION OF PYRAZOLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2021/006267
Kind Code:
A1
Abstract:
(1) An alkyl sulfate ester salt or an alkyl sulfonic acid salt of a pyrazole derivative represented by general formula (I) [where: R represents hydrogen, an optionally substituted chain-form or cyclic hydrocarbon group or an optionally substituted heterocyclic group; and Ar1 and Ar2 are the same or different and represent an optionally substituted homo- or heterocyclic group], (2) a solid dispersion preparation or a self-emulsifiable preparation of a salt of a pyrazole derivative represented by general formula (I), (3) a solid dispersion preparation or a self-emulsifiable preparation of a pyrazole derivative represented by general formula (I) in a free state, or (4) a pharmaceutical composition comprising any of (1) to (3) is pharmaceutically effective as a medicine.
Inventors:
SUGIMOTO HACHIRO (JP)
OKUDA MICHIAKI (JP)
NAKANO MASATO (JP)
TAKAMI MAKO (JP)
OKUDA MICHIAKI (JP)
NAKANO MASATO (JP)
TAKAMI MAKO (JP)
Application Number:
PCT/JP2020/026541
Publication Date:
January 14, 2021
Filing Date:
July 07, 2020
Export Citation:
Assignee:
GREEN TECHNOLOGY CO LTD (JP)
International Classes:
A61P21/02; A61K9/14; A61K9/20; A61K31/4439; A61K47/20; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P43/00; C07D401/14
Domestic Patent References:
| WO2014057772A1 | 2014-04-17 | |||
| WO2012141228A1 | 2012-10-18 | |||
| WO2016140219A1 | 2016-09-09 |
Foreign References:
| JP2015500306A | 2015-01-05 | |||
| JP2017500332A | 2017-01-05 | |||
| JP2017503866A | 2017-02-02 | |||
| JP2014530875A | 2014-11-20 |
Attorney, Agent or Firm:
IWATANI Ryo (JP)
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