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Title:
SELECTIVE ESTROGEN RECEPTOR MODULATORS
Document Type and Number:
WIPO Patent Application WO/2004/058682
Kind Code:
A1
Abstract:
Compounds represented by the general formula (I), salts thereof, and hydrates of both: (I) wherein T is a single bond, optionally substituted C1-4 alkylene, or the like; the symbols &dot &dot &dot &dot &dot &dot are each a single bond or a double bond; A is a single bond, a divalent group derived from a 5- to 14-membered heterocycle which may be substituted, or the like; Y is a single bond or the like; Z is methylene or the like; G is phenylene optionally fused with a 5- or 6-membered ring which may have a heteroatom, or the like; Ra and Rb are each independently hydrogen or the like; W is a single bond or the like; R’ represents one to four independent hydrogen atoms or the like; and R” represents one to four independent hydrogen atoms or the like.

Inventors:
HAMAOKA SHINICHI (JP)
KITAZAWA NORITAKA (JP)
NARA KAZUMASA (JP)
SASAKI ATSUSHI (JP)
KAMADA ATSUSHI (JP)
OKABE TADASHI (JP)
Application Number:
PCT/JP2003/016808
Publication Date:
July 15, 2004
Filing Date:
December 25, 2003
Export Citation:
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Assignee:
EISAI CO LTD (JP)
HAMAOKA SHINICHI (JP)
KITAZAWA NORITAKA (JP)
NARA KAZUMASA (JP)
SASAKI ATSUSHI (JP)
KAMADA ATSUSHI (JP)
OKABE TADASHI (JP)
International Classes:
A61P3/06; A61P9/10; A61P15/00; A61P15/12; A61P19/10; A61P21/00; A61P25/00; A61P25/28; A61P35/00; A61P43/00; C07C215/78; C07C217/18; C07C217/22; C07C217/78; C07C217/84; C07C219/34; C07C323/25; C07D295/088; C07D311/58; C07F5/02; C07F7/18; C07F7/22; (IPC1-7): C07C215/74; A61K31/136; A61K31/137; A61K31/138; A61K31/222; A61K31/341; A61K31/352; A61K31/36; A61K31/381; A61K31/397; A61K31/40; A61K31/403; A61K31/404; A61K31/439; A61K31/4409; A61K31/445; A61K31/4453; A61K31/4465; A61K31/4468; A61K31/454; A61K31/46; A61K31/55; A61P3/06; A61P9/10; A61P15/00; A61P15/12; A61P19/10; A61P21/00; A61P25/00; A61P25/28; A61P35/00; A61P43/00; C07C215/78; C07C217/14; C07C217/58; C07C217/80; C07C217/84; C07C217/94; C07C219/34; C07C229/34; C07C235/56; C07C271/16; C07C323/25; C07D205/04; C07D207/04; C07D209/08; C07D209/14; C07D209/30; C07D209/38; C07D209/44; C07D209/48; C07D211/14; C07D211/26; C07D211/46; C07D211/58; C07D213/36; C07D213/64; C07D213/73; C07D223/04; C07D223/16; C07D277/66; C07D295/08; C07D295/12; C07D307/14; C07D311/58; C07D317/62; C07D317/66; C07D333/20; C07D333/58; C07D451/06; C07D453/02; C07F7/10
Domestic Patent References:
WO2001032631A22001-05-10
WO2002016316A12002-02-28
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EP0406734A21991-01-09
JPH0324069A1991-02-01
EP0226508A11987-06-24
DE2909754A11980-09-18
EP1199069A22002-04-24
US4418068A1983-11-29
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US6204286B12001-03-20
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EP0285287A21988-10-05
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Attorney, Agent or Firm:
Inaba, Yoshiyuki (23rd Floor Roppongi Hills Mori Tower, 6-10-1, Roppong, Minato-ku Tokyo, JP)
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