SIX-MEMBERED RING-CONTAINING NUCLEOSIDE COMPOUND AND PREPARATION METHOD THEREFOR

Title:

SIX-MEMBERED RING-CONTAINING NUCLEOSIDE COMPOUND AND PREPARATION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2021/217685

Kind Code:

A1

Abstract:

A six-membered ring-containing nucleoside compound 7 and a preparation method therefor. The structural formula of the compound 7 is (I), wherein R1 is selected from one of (II), (III), (IV), and (V), and R2 is hydroxyl or alkynyl.

Inventors:

HU MIN (CN)
HONG DONGCHUN (CN)
XUE WEIMIN (CN)

Application Number:

PCT/CN2020/088682

Publication Date:

November 04, 2021

Filing Date:

May 06, 2020

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Assignee:

NANTONG WEISHUN BIOTECHNOLOGY CO LTD (CN)

International Classes:

C07H19/052; A61P31/12; A61P31/14; C07H19/06; C07H19/23

Foreign References:

CN107074902A	2017-08-18
CN106029644A	2016-10-12
CN110330540A	2019-10-15

Other References:

DOWNEY A. MICHAEL, RICHTER CELIN, POHL RADEK, MAHRWALD RAINER, HOCEK MICHAL: "Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose", ORGANIC LETTERS, vol. 17, no. 18, 10 September 2015 (2015-09-10), US, pages 4604 - 4607, XP055861742, ISSN: 1523-7052, DOI: 10.1021/acs.orglett.5b02332

Attorney, Agent or Firm:

SHANGHAI WEICE INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)

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