Title:
SMALL MOLECULE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2021/078022
Kind Code:
A1
Abstract:
Provided in the present invention is a small molecule compound, which is characterized in that it is a compound or a stereoisomer, geometric isomer, tautomer, racemate, hydrate, solvate, metabolite, and pharmaceutically acceptable salt or prodrug of the compound as represented by the following structural formula: formula (I). The small molecule compound of the present invention is applicable as a highly efficient and specific JAK kinase inhibitor, specifically a Tyk2 inhibitor, and/or a JAK1 inhibitor, and/or a JAK1/Tyk2 dual inhibitor.
Inventors:
XING LI (CN)
LI GUANQUN (CN)
WANG XIAOLEI (CN)
CAI YUTING (CN)
JIANG XIANG (CN)
PAN XIANG (CN)
ZHU WENHAO (CN)
WANG YANG (CN)
WANG ZENGQUAN (CN)
LI GUANQUN (CN)
WANG XIAOLEI (CN)
CAI YUTING (CN)
JIANG XIANG (CN)
PAN XIANG (CN)
ZHU WENHAO (CN)
WANG YANG (CN)
WANG ZENGQUAN (CN)
Application Number:
PCT/CN2020/120132
Publication Date:
April 29, 2021
Filing Date:
October 10, 2020
Export Citation:
Assignee:
TECHNODERMA MEDICINES PTE LTD (CN)
International Classes:
C07D403/14; A61K31/506; A61P17/00; A61P19/02; A61P29/00; A61P37/06; C07D401/14; C07D403/12; C07D405/14
Domestic Patent References:
| WO2014111037A1 | 2014-07-24 |
Foreign References:
| CN110862380A | 2020-03-06 | |||
| CN103298794A | 2013-09-11 | |||
| CN110330484A | 2019-10-15 | |||
| CN105189480A | 2015-12-23 | |||
| CN103119025A | 2013-05-22 |
Attorney, Agent or Firm:
SHANGHAI CPTO INTELLECTUAL PROPERTY AGENCY CO.LTD (CN)
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