Title:
SOLID FORM OF MACROCYCLIC COMPOUND, PREPARATION THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/233296
Kind Code:
A1
Abstract:
The present invention relates to a crystalline form of a free base of a compound of formula (A) (compound A) or a pharmaceutically acceptable salt thereof, a preparation method therefor, and use of the compound in the preparation of a medicament for treating and/or preventing diseases mediated by ALK kinase and mutants thereof, such as cell proliferative diseases, inflammation, infections, immunological diseases, organ transplantation, viral diseases, cardiovascular diseases or metabolic diseases.
Inventors:
WANG YIHAN (CN)
LI HUANYIN (CN)
LI HUANYIN (CN)
Application Number:
PCT/CN2021/094362
Publication Date:
November 25, 2021
Filing Date:
May 18, 2021
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
A61K31/439; C07D498/18; A61P3/00; A61P9/00; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P37/00; A61P37/06
Domestic Patent References:
WO2017148325A1 | 2017-09-08 |
Foreign References:
CN111233833A | 2020-06-05 | |||
CN110407856A | 2019-11-05 | |||
CN109152738A | 2019-01-04 | |||
CN201780013374A | 2017-02-23 | |||
CN108699081A | 2018-10-23 | |||
US201716081611A | 2017-02-23 | |||
US10543199B2 | 2020-01-28 | |||
EP17759176A | 2017-02-23 | |||
JP2018545928A | 2017-02-23 |
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
Download PDF: