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Title:
SOLID FORMS OF SOFOSBUVIR
Document Type and Number:
WIPO Patent Application WO/2016/038542
Kind Code:
A3
Abstract:
The present disclosure provides crystalline sofosbuvir form-M1 and amorphous solid dispersion of sofosbuvir. The present disclosure also provides a process for the preparation of the amorphous form of sofosbuvir, the crystalline form of sofosbuvir, and amorphous solid dispersion of sofosbuvir and one or more pharmaceutically acceptable carriers.

Inventors:
JETTI RAMAKOTESWARA RAO (IN)
GORANTLA ASHARANI (IN)
BEERAVELLY SATISH (IN)
BHAGAVATULA NEELIMA (IN)
SINGH AMIT (IN)
JAYACHANDRA SURESHBABU (IN)
KAUSHIK VIPIN KUMAR (IN)
RAVI VIJAYA KRISHANA (IN)
VAKITI SRINIVAS (IN)
RAO POTLA VENKATA SRINIVAS (IN)
Application Number:
PCT/IB2015/056893
Publication Date:
May 12, 2016
Filing Date:
September 09, 2015
Export Citation:
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Assignee:
MYLAN LAB LTD (IN)
International Classes:
A61K47/32; A61K9/14; A61K9/16; A61K31/664; A61K31/7072; A61P31/14; C07F9/6558; C07H19/06; C07H19/10
Domestic Patent References:
WO2015150561A22015-10-08
WO2013101550A12013-07-04
Foreign References:
US20140212491A12014-07-31
Other References:
VO CHAU LE-NGOC ET AL: "Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 85, no. 3, 18 September 2013 (2013-09-18), pages 799 - 813, XP028791016, ISSN: 0939-6411, DOI: 10.1016/J.EJPB.2013.09.007
Attorney, Agent or Firm:
SINGH, Manisha (709-710 Tolstoy House,15-17, Tolstoy Marg, New Delhi 1, IN)
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