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Patent Searching and Data


Title:
SPIRO COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/105636
Kind Code:
A1
Abstract:
Disclosed are a spiro compound, a pharmaceutical composition containing same, and the use thereof. The spiro compound interferes with interaction between the protein menin and MLL1, MLL2 or MLL fusion oncoproteins, and is expected to be used for a drug for the treatment of tumors, diabetes and other diseases that depend on the activity of MLL1, MLL2 or MLL fusion proteins, and/or the protein menin.

Inventors:
CHEN XUXING (CN)
LI JING (CN)
CHEN YANHONG (CN)
ZHAO ZHAO (CN)
Application Number:
PCT/CN2021/129425
Publication Date:
May 27, 2022
Filing Date:
November 09, 2021
Export Citation:
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Assignee:
SHANGHAI EUREGEN BIOPHARMA CO LTD (CN)
International Classes:
C07D401/14; A61K31/506; A61P35/00; A61P35/02; C07D403/14; C07D419/14
Foreign References:
CN109743875A2019-05-10
US20200216471A12020-07-09
CN107922378A2018-04-17
CN109715634A2019-05-03
CN109689663A2019-04-26
CN110691779A2020-01-14
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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