Title:
STABILISATION OF NUCLEIC ACIDS
Document Type and Number:
WIPO Patent Application WO2004013155
Kind Code:
A3
Abstract:
A method for the stabilisation of nucleic acid from a biological sample, which comprises: (a) collecting of biological sample; (b) treating the sample so that a proportion of the 2', 3' or 5' -OH positions of the nucleic acid are modified with a protecting group; and (c) subjecting the treated sample to one or more steps to isolate nucleic acid therefrom; wherein the modified nucleic acid is subjected to a deprotection step comprising treatment with a primary amine to remove the protecting group.
Inventors:
GOLDSBOROUGH ANDREW SIMON (FR)
Application Number:
PCT/GB2003/003131
Publication Date:
April 08, 2004
Filing Date:
July 18, 2003
Export Citation:
Assignee:
CYCLOPS GENOME SCIENCES LTD (GB)
GOLDSBOROUGH ANDREW SIMON (FR)
GOLDSBOROUGH ANDREW SIMON (FR)
International Classes:
C12N15/10; C07H21/00; (IPC1-7): C12N15/10
Domestic Patent References:
| WO2000075302A2 | 2000-12-14 | |||
| WO2001094626A1 | 2001-12-13 |
Foreign References:
| US5804683A | 1998-09-08 |
Other References:
J.H.BOAL ET AL.: "Cleavage of Oligodeoxyribonucleotides from controlled-pore glass supports and their rapid deprotection.", NUCLEIC ACIDS RESEARCH., vol. 15, 1996, OXFORD UNIVERSITY PRESS, SURREY., GB, pages 3115 - 3117, XP002267799, ISSN: 0305-1048
Download PDF:
Previous Patent: MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY
Next Patent: REDUCING NgR-p75 MEDIATED BY INHIBITION OF AXON REGENERATION
Next Patent: REDUCING NgR-p75 MEDIATED BY INHIBITION OF AXON REGENERATION