STABLE FORMULATIONS OF FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN

Title:

STABLE FORMULATIONS OF FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND TO MYOSTATIN

Document Type and Number:

WIPO Patent Application WO/2018/204617

Kind Code:

A8

Abstract:

The present invention relates generally to stable liquid formulations comprising polypeptides with 10Fn3 domains which bind to myostatin and unit dosage forms thereof for administration various routes, including subcutaneous (SC), for treating muscle- wasting and metabolic disorders.

Inventors:

NASHINE VISHAL (US)
PATEL RUSHIKESH (US)

Application Number:

PCT/US2018/030851

Publication Date:

January 03, 2019

Filing Date:

May 03, 2018

Export Citation:

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Assignee:

BRISTOL MYERS SQUIBB CO (US)

International Classes:

A61K9/08; A61K38/39; A61K47/18; A61K47/26; A61P21/00

Attorney, Agent or Firm:

REMILLARD, Jane, E. et al. (US)

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