Title:
STABLE HYBRID FC FUSION G-CSF FORMULATION
Document Type and Number:
WIPO Patent Application WO/2019/212429
Kind Code:
A3
Abstract:
The present invention comprises a stable form of hybrid Fc fused Granulocyte Colony Stimulating Factor (G-CSF)formulation comprising (i) a therapeutically effective amount of hybrid Fc fusion G-CSF, (ii) a buffer system, (iii) at least one stabilizerand (iv) at least one surfactant, and (v) optionally propylene glycol as organic solvent, suitable for administration via a subcutaneous (SC) route.
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Inventors:
ÖNCEL HATICE (TR)
ÇAPAN YILMAZ (TR)
DAĞLIKOCA DUYGU (TR)
ERDOĞAN DAĞDAŞ HURIYE (TR)
ŞAHİN ADEM (TR)
ÇORBACIOĞLU MELTEM (TR)
ÖZKAN AYLIN (TR)
SARRAÇOĞLU NAGEHAN (TR)
ÇAPAN YILMAZ (TR)
DAĞLIKOCA DUYGU (TR)
ERDOĞAN DAĞDAŞ HURIYE (TR)
ŞAHİN ADEM (TR)
ÇORBACIOĞLU MELTEM (TR)
ÖZKAN AYLIN (TR)
SARRAÇOĞLU NAGEHAN (TR)
Application Number:
PCT/TR2018/050208
Publication Date:
March 12, 2020
Filing Date:
May 04, 2018
Export Citation:
Assignee:
ILKOGEN ILAC SANAYI VE TICARET A S (TR)
International Classes:
A61K9/00; A61K9/08; A61K38/19; A61K47/02; A61K47/10
Domestic Patent References:
WO2012165917A1 | 2012-12-06 |
Foreign References:
US20030082679A1 | 2003-05-01 | |||
US20160362473A1 | 2016-12-15 | |||
US8586048B2 | 2013-11-19 |
Attorney, Agent or Firm:
BULUT, Pınar (TR)
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