Title:
STAMBOMYCIN AND DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS DRUGS
Document Type and Number:
WIPO Patent Application WO/2011/009938
Kind Code:
A3
Abstract:
The present invention relates to Stambomycin compounds, their derivatives and their pharmaceutically acceptable salt thereof.
Inventors:
AIGLE BERTRAND (FR)
CHALLIS GREGORY (GB)
LAURETI LUISA (FR)
SONG LIJIANG (GB)
LEBLOND PIERRE (FR)
CHALLIS GREGORY (GB)
LAURETI LUISA (FR)
SONG LIJIANG (GB)
LEBLOND PIERRE (FR)
Application Number:
PCT/EP2010/060707
Publication Date:
May 05, 2011
Filing Date:
July 23, 2010
Export Citation:
Assignee:
UNIV NANCY 1 HENRI POINCARE (FR)
UNIV WARWICK (GB)
AGRONOMIQUE INST NAT RECH (FR)
AIGLE BERTRAND (FR)
CHALLIS GREGORY (GB)
LAURETI LUISA (FR)
SONG LIJIANG (GB)
LEBLOND PIERRE (FR)
UNIV WARWICK (GB)
AGRONOMIQUE INST NAT RECH (FR)
AIGLE BERTRAND (FR)
CHALLIS GREGORY (GB)
LAURETI LUISA (FR)
SONG LIJIANG (GB)
LEBLOND PIERRE (FR)
International Classes:
C07H17/08; C12N1/20; C12N15/76; C12P19/62; C12R1/465
Domestic Patent References:
WO2000000618A2 | 2000-01-06 |
Other References:
CHALLIS GREGORY L: "Mining microbial genomes for new natural products and biosynthetic pathways", MICROBIOLOGY (READING), vol. 154, no. Part 6, June 2008 (2008-06-01), pages 1555 - 1569, XP002585719, ISSN: 1350-0872
YADAV GITANJALI ET AL: "SEARCHPKS: A program for detection and analysis of polyketide synthase domains", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB LNKD- DOI:10.1093/NAR/GKG607, vol. 31, no. 13, 1 July 2003 (2003-07-01), pages 3654 - 3658, XP002517616, ISSN: 1362-4962
KARRAY FATMA ET AL: "Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB LNKD- DOI:10.1099/MIC.0.2007/009746-0, vol. 153, no. Part 12, 1 December 2007 (2007-12-01), pages 4111 - 4122, XP002481781, ISSN: 1350-0872
CHOULET FREDERIC ET AL: "Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens", JOURNAL OF BACTERIOLOGY, vol. 188, no. 18, September 2006 (2006-09-01), pages 6599 - 6610, XP002585720, ISSN: 0021-9193
BARONA-GOMEZ FRANCISCO ET AL: "Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877", MICROBIOLOGY (READING), vol. 152, no. Part 11, November 2006 (2006-11-01), pages 3355 - 3366, XP002585721, ISSN: 1350-0872
See also references of EP 2456777A2
YADAV GITANJALI ET AL: "SEARCHPKS: A program for detection and analysis of polyketide synthase domains", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB LNKD- DOI:10.1093/NAR/GKG607, vol. 31, no. 13, 1 July 2003 (2003-07-01), pages 3654 - 3658, XP002517616, ISSN: 1362-4962
KARRAY FATMA ET AL: "Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB LNKD- DOI:10.1099/MIC.0.2007/009746-0, vol. 153, no. Part 12, 1 December 2007 (2007-12-01), pages 4111 - 4122, XP002481781, ISSN: 1350-0872
CHOULET FREDERIC ET AL: "Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens", JOURNAL OF BACTERIOLOGY, vol. 188, no. 18, September 2006 (2006-09-01), pages 6599 - 6610, XP002585720, ISSN: 0021-9193
BARONA-GOMEZ FRANCISCO ET AL: "Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877", MICROBIOLOGY (READING), vol. 152, no. Part 11, November 2006 (2006-11-01), pages 3355 - 3366, XP002585721, ISSN: 1350-0872
See also references of EP 2456777A2
Attorney, Agent or Firm:
MOUGET-GONIOT, Claire et al. (Paris, Paris, FR)
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