Title:
STEROID DERIVATIVE FXR AGONIST
Document Type and Number:
WIPO Patent Application WO/2017/129125
Kind Code:
A1
Abstract:
The present invention relates to a compound represented by formula (I), a tautomer thereof or a pharmaceutically acceptable salt thereof, and relates to applications thereof in the preparation of drugs for treating FXR related diseases.
Inventors:
HE HAIYING (CN)
XIAO HUALING (CN)
LI PENG (CN)
DU CHUNYAN (CN)
LUO ZHI (CN)
CHEN SHUHUI (CN)
XIAO HUALING (CN)
LI PENG (CN)
DU CHUNYAN (CN)
LUO ZHI (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2017/072567
Publication Date:
August 03, 2017
Filing Date:
January 25, 2017
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
MEDSHINE DISCOVERY INC (CN)
MEDSHINE DISCOVERY INC (CN)
International Classes:
A61K31/575; C07J43/00; A61K31/58; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P13/02; C07J9/00; C07J31/00; C07J33/00
Domestic Patent References:
WO2002072598A1 | 2002-09-19 | |||
WO2005082925A2 | 2005-09-09 | |||
WO2016173397A1 | 2016-11-03 | |||
WO2016086134A1 | 2016-06-02 | |||
WO2016086218A1 | 2016-06-02 | |||
WO2016161003A1 | 2016-10-06 | |||
WO2000037077A1 | 2000-06-29 | |||
WO2005082925A2 | 2005-09-09 |
Foreign References:
CN106083978A | 2016-11-09 |
Other References:
BM. FORMAN, CELL, vol. 81, 1995, pages 687 - 693
DJ. MANGELSDORF ET AL., CELL, vol. 83, 1995, pages 841 - 850
BM. FORMAN ET AL., CELL, vol. 81, 1995, pages 687 - 693
W. SEOL ET AL., MOL. ENDOCRINNOL., vol. 9, 1995, pages 72 - 85
MAEHR, J. CHEM. ED., vol. 62, 1985, pages 114 - 120
"Remington: The Science and Practice of Pharmacy", 2005, LIPPINCOTT, WILLIAMS & WILKINS
"Protective Groups In Organic Synthesis", 1991, WILEY AND SONS
See also references of EP 3409684A4
DJ. MANGELSDORF ET AL., CELL, vol. 83, 1995, pages 841 - 850
BM. FORMAN ET AL., CELL, vol. 81, 1995, pages 687 - 693
W. SEOL ET AL., MOL. ENDOCRINNOL., vol. 9, 1995, pages 72 - 85
MAEHR, J. CHEM. ED., vol. 62, 1985, pages 114 - 120
"Remington: The Science and Practice of Pharmacy", 2005, LIPPINCOTT, WILLIAMS & WILKINS
"Protective Groups In Organic Synthesis", 1991, WILEY AND SONS
See also references of EP 3409684A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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