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Title:
STRETCHABLE NANOFIBER MEMBRANE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/161505
Kind Code:
A1
Abstract:
The present application relates to the technical field of the preparation of medical nanofiber materials. In particular, disclosed are a stretchable nanofiber membrane, a preparation method therefor and the application thereof. The stretchable nanofiber membrane has a core-shell structure, involving a core layer that comprises an aminated chitosan carrier and an anti-microbial drug doped in the aminated chitosan carrier; and a shell layer that comprises a polyurethane carrier, poly(N-isopropylacrylamide) and N-TiO2/activated carbon, wherein poly(N-isopropylacrylamide) and N-TiO2/activated carbon are doped in the polyurethane carrier. The stretchable nanofiber membrane can be prepared by means of a coaxial electrostatic spinning technique. The nanofiber membrane prepared by the present application has the advantages of having excellent tensile properties, high adsorption properties, an extended anti-microbial period and being self-cleaning, can significantly improve a wound surface healing effect, and has broad application prospects in the field of medical dressings.

Inventors:
XU JIANLIN (CN)
LIU RUINING (CN)
Application Number:
PCT/CN2022/075825
Publication Date:
August 04, 2022
Filing Date:
February 10, 2022
Export Citation:
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Assignee:
HEBEI NINGFANG GROUP CO LTD (CN)
International Classes:
A61L15/44; A61L15/26; A61L15/28; A61L15/42; A61L15/46; D01F1/00; D01F8/10; D01F8/16; D01F8/18; D04H1/728
Domestic Patent References:
WO2018090925A12018-05-24
Foreign References:
CN112999404A2021-06-22
CN103611182A2014-03-05
CN102733088A2012-10-17
CN109453799A2019-03-12
CN111455564A2020-07-28
CN111424425A2020-07-17
Attorney, Agent or Firm:
HEBEI GUOWEIZHIYUAN INTELLECTUAL PROPERTY AGENCY CO.,LTD (CN)
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