Title:
SUBCUTANEOUSLY IMPLANTED DEVICE FOR GASTROINTESTINAL ADMINISTRATION OF SUBSTANCES
Document Type and Number:
WIPO Patent Application WO/2020/128831
Kind Code:
A3
Abstract:
A method includes using a subcutaneously-implanted pump to deliver to a portion of a gastrointestinal tract a formulation including a levodopa compound and a carbidopa compound which provides a treatment for a neurological disease, such as Parkinson's disease.
Inventors:
HELDMAN ELI (IL)
KUSHNIR MOSHE (IL)
YOUDIM TAL (IL)
KUSHNIR MOSHE (IL)
YOUDIM TAL (IL)
Application Number:
PCT/IB2019/060921
Publication Date:
September 10, 2020
Filing Date:
December 17, 2019
Export Citation:
Assignee:
ENDOPUMP LTD (IL)
International Classes:
A61K47/10; A61K31/198; A61K47/32
Foreign References:
| US20140088192A1 | 2014-03-27 |
Other References:
ABDELWAHED W; DEGOBERT G; STAINMESSE S; FESSI H: "Freeze-drying of nanoparticles: Formulation, process and storage considerations", ADVANCED DRUG DELIVERY REVIEWS, vol. 58, 6 October 2016 (2016-10-06), pages 1688 - 1713, XP024892085, ISSN: 0169-409X, DOI: 10.1016/j.addr.2006.09.017
ANONYMOUS: "Use Caution with Implanted Pumps for Intrathecal Administration of Medicines for Pain Management: FDA Safety Communication", USE CAUTION WITH IMPLANTED PUMPS FOR INTRATHECAL ADMINISTRATION OF MEDICINES FOR PAIN MANAGEMENT: FDA SAFETY COMMUNICATION, 14 November 2018 (2018-11-14), pages 1 - 6, XP055735811, Retrieved from the Internet
ANONYMOUS: "Vortex Mixer", 10 August 2016 (2016-08-10), pages 1 - 2, XP055735812, Retrieved from the Internet
THOMAS MÜLLER: "The Impact of COMT-inhibition on Gastrointestinal Levodopa Absorption in Patients with Parkinson's Disease", CLINICAL MEDICINE INSIGHTS: THERAPEUTICS, vol. 2, 17 March 2010 (2010-03-17), pages 155 - 168, XP055735818, ISSN: 1179-559X, DOI: 10.4137/CMT.S1169
ANONYMOUS: "Sonication", 22 May 2018 (2018-05-22), pages 1 - 2, XP002626906, Retrieved from the Internet
ANONYMOUS: "Temperature dependence of viscosity", 21 March 2017 (2017-03-21), pages 1 - 8, XP055735826, Retrieved from the Internet
ANONYMOUS: "Use Caution with Implanted Pumps for Intrathecal Administration of Medicines for Pain Management: FDA Safety Communication", USE CAUTION WITH IMPLANTED PUMPS FOR INTRATHECAL ADMINISTRATION OF MEDICINES FOR PAIN MANAGEMENT: FDA SAFETY COMMUNICATION, 14 November 2018 (2018-11-14), pages 1 - 6, XP055735811, Retrieved from the Internet
ANONYMOUS: "Vortex Mixer", 10 August 2016 (2016-08-10), pages 1 - 2, XP055735812, Retrieved from the Internet
THOMAS MÜLLER: "The Impact of COMT-inhibition on Gastrointestinal Levodopa Absorption in Patients with Parkinson's Disease", CLINICAL MEDICINE INSIGHTS: THERAPEUTICS, vol. 2, 17 March 2010 (2010-03-17), pages 155 - 168, XP055735818, ISSN: 1179-559X, DOI: 10.4137/CMT.S1169
ANONYMOUS: "Sonication", 22 May 2018 (2018-05-22), pages 1 - 2, XP002626906, Retrieved from the Internet
ANONYMOUS: "Temperature dependence of viscosity", 21 March 2017 (2017-03-21), pages 1 - 8, XP055735826, Retrieved from the Internet
Attorney, Agent or Firm:
KLEIN, David (IL)
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