Title:
SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS
Document Type and Number:
WIPO Patent Application WO2004083208
Kind Code:
A8
Abstract:
The present invention relates to novel substituted piperidine and piperazine derivatives as melanocortin-4 receptor (MC-4R) modulators. MC-4R agonists of the invention can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the MC-4R antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. All diseases and disorders, where the regulation of the MC-4R is involved, can be treated with the compounds of the invention.
Inventors:
SOEBERDT MICHAEL (DE)
WEYERMANN PHILIPP (CH)
VON SPRECHER ANDREAS (CH)
HENNEBOEHLE MARCO (DE)
WEYERMANN PHILIPP (CH)
VON SPRECHER ANDREAS (CH)
HENNEBOEHLE MARCO (DE)
Application Number:
PCT/EP2004/002896
Publication Date:
January 20, 2005
Filing Date:
March 19, 2004
Export Citation:
Assignee:
MYOCONTRACT LTD (CH)
SOEBERDT MICHAEL (DE)
WEYERMANN PHILIPP (CH)
VON SPRECHER ANDREAS (CH)
HENNEBOEHLE MARCO (DE)
SOEBERDT MICHAEL (DE)
WEYERMANN PHILIPP (CH)
VON SPRECHER ANDREAS (CH)
HENNEBOEHLE MARCO (DE)
International Classes:
A61K31/451; A61K31/4725; A61P3/04; A61P15/00; A61P25/22; A61P25/24; C07D207/27; C07D211/60; C07D211/62; C07D295/12; C07D401/06; C07D401/10; C07D401/12; C07D401/14; C07D405/14; C07D471/10; C07D521/00; C07D207/26; (IPC1-7): C07D471/10; C07D401/12; C07D521/00; C07D211/62; C07D295/12; A61K31/451; A61K31/4725; A61P3/04; A61P15/00; A61P25/22; A61P25/24
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