SUBSTITUTED TETRACYCLINE COMPOUNDS

Title:

SUBSTITUTED TETRACYCLINE COMPOUNDS

Document Type and Number:

WIPO Patent Application WO2005009943

Kind Code:

A3

Abstract:

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

Inventors:

NELSON MARK L (US)
OHEMENG KWASI (US)
AMOO VICTOR
KIM OAK (US)
ABATO PAUL (US)
ASSEFA HAREGEWEIN (US)
BERNIAC JOEL (US)
BHATIA BEENA (US)
BOWSER TODD (US)
CHEN JACKSON (US)
GRIER MARK (US)
HOHOS AARON
HONEYMAN LAURA (US)
ISMAIL MOHAMED Y (US)
MECHICHE RACHID
NIHLAWI MOHAMMED (US)
SIZENSKY EMMANUELLE (US)

Application Number:

PCT/US2004/020249

Publication Date:

June 16, 2005

Filing Date:

June 25, 2004

Export Citation:

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Assignee:

PARATEK PHARM INNC (US)
NELSON MARK L (US)
OHEMENG KWASI (US)
AMOO VICTOR
KIM OAK (US)
ABATO PAUL (US)
ASSEFA HAREGEWEIN (US)
BERNIAC JOEL (US)
BHATIA BEENA (US)
BOWSER TODD (US)
CHEN JACKSON (US)
GRIER MARK (US)
HOHOS AARON
HONEYMAN LAURA (US)
ISMAIL MOHAMED Y (US)
MECHICHE RACHID
NIHLAWI MOHAMMED (US)
SIZENSKY EMMANUELLE (US)

International Classes:

C07C237/26; C07C271/22; C07C271/54; C07C275/28; C07C275/30; (IPC1-7): C07C237/26; A61K31/65

Domestic Patent References:

WO2002072031A2	2002-09-19
WO2002085303A2	2002-10-31
WO2002072532A1	2002-09-19
WO2003005971A2	2003-01-23
WO2004038000A2	2004-05-06
WO2004038001A2	2004-05-06

Foreign References:

US20020193354A1

2002-12-19

Other References: