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Title:
SUBUNIT OPTIMIZED FUSION PROTEINS
Document Type and Number:
WIPO Patent Application WO2001019842
Kind Code:
A9
Abstract:
A method of making a fusion protein having: a first member, fused to a second member wherein the first and second members are chosen such that the fusion protein assembles into a complex having a number of subunits which optimizes activity of the multimeric form of the second member.

Inventors:
POLLOCK DAN (US)
MEADE HARRY M (US)
BOSSLET KLAUS (DE)
Application Number:
PCT/US2000/025558
Publication Date:
November 14, 2002
Filing Date:
September 18, 2000
Export Citation:
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Assignee:
GENZYME TRANSGENICS CORP (US)
POLLOCK DAN (US)
MEADE HARRY M (US)
BOSSLET KLAUS (DE)
International Classes:
C12N15/09; A61K38/43; A61P35/00; C07H21/02; C07K16/30; C07K19/00; C12N5/00; C12N5/02; C12N9/24; C12N15/62; (IPC1-7): C07H21/02; C07H21/04; C12N5/00; C12N5/02; C12N15/00; C12N15/09; C12N15/63; C12N15/70; C12N15/74; C07K1/00; C07K14/00; C07K16/00; C07K17/00; C08H1/00; C12P21/00; A01K67/00; A01K67/033
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