Title:
SULFONAMIDE INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/143695
Kind Code:
A1
Abstract:
The present invention relates to a sulfonamide inhibitor, and a preparation method therefor and an application thereof. Specifically, the compound of the present invention has a structure as represented by formula (I). Also disclosed in the present invention are a preparation method for the compound and an application thereof as an AhR inhibitor. The compound of the present invention has a good selective inhibitory effect on AhR, and has better pharmacodynamic and pharmacokinetic properties, and lower toxic and side effects.
Inventors:
LV BINHUA (CN)
CUI DAWEI (CN)
LIU LIANJUN (CN)
PANG XUDONG (CN)
CUI DAWEI (CN)
LIU LIANJUN (CN)
PANG XUDONG (CN)
Application Number:
PCT/CN2021/142177
Publication Date:
July 07, 2022
Filing Date:
December 28, 2021
Export Citation:
Assignee:
SUZHOU ZELGEN BIOPHARMACEUTICALS CO LTD (CN)
SHANGHAI ZELGEN PHARMA TECH CO LTD (CN)
SHANGHAI ZELGEN PHARMA TECH CO LTD (CN)
International Classes:
C07D401/12; A61K31/501; A61P35/00; C07D237/16; C07D237/20; C07D405/12
Domestic Patent References:
| WO2020201825A2 | 2020-10-08 | |||
| WO2019101643A1 | 2019-05-31 | |||
| WO2019101642A1 | 2019-05-31 |
Foreign References:
| CN111592528A | 2020-08-28 | |||
| CN109863140A | 2019-06-07 | |||
| CN110678459A | 2020-01-10 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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