SURFACE-DRUG-LOADING INFLATABLE BALLOON FOR VERTEBROPLASTY AND PREPARATION METHOD THEREFOR

WIPO Patent Application WO/2020/244388

A1

Disclosed are a surface-drug-loading inflatable balloon for vertebroplasty and a preparation method therefor, wherein same comprises a balloon body and a drug-loading film attached to the surface of the balloon body. The drug-loading film consists of at least two drug-loading coating layers, and the first drug-loading coating layer directly in contact with the balloon body is formed by means of electrospinning. In the present invention, the surface of the balloon body is provided with the drug-loading film, and the drug-loading film consists of a plurality of drug-loading coating layers. The drug-loading film can be retained in the body after the balloon is withdrawn and forms an outer shell enclosing bone cement, playing the role of effectively releasing the drug at the desired sites, improving the efficiency of the drug, and also preventing the bone cement from leaving the positions thereof. Due to multiple functions, the inflatable balloon improves postoperative effects of percutaneous vertebroplasty and percutaneous kyphoplasty, and is especially suitable for the treatment of osteoporosis and related compression fractures.

ZHANG HAIJUN (CN)
SUN GANG (CN)
TIAN ZHENFAN (CN)
HOU WENBO (CN)
ZHOU CHAO (CN)
YIN YUXIA (CN)
LU SHOUTAO (CN)
LIU GUANG (CN)

PCT/CN2020/091478

December 10, 2020

May 21, 2020

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SHANDONG BRANDEN MEDICAL DEVICE CO LTD (CN)

A61B17/88; A61M25/10; A61M29/04

CN110141760A	2019-08-20
CN106618714A	2017-05-10
CN103251449A	2013-08-21
US20160157898A1	2016-06-09
EP0836435B1	2004-09-01
US20140128877A1	2014-05-08

JINAN SPRINGS PATENT&TRADEMARK OFFICE (CN)

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