Title:
SYNERGISTIC COMBINATIONS OF POLYENE FUNGICIDES AND NON-RIBOSOMAL PEPTIDES AND RELATED METHODS OF USE
Document Type and Number:
WIPO Patent Application WO/2012/162412
Kind Code:
A3
Abstract:
The present invention includes compositions comprising a synergistic fungicidal combination of a polyene fungicide and at least, one lipopeptide and methods for using such compositions in controlling fungal pathogens.
Inventors:
GUILHABERT-GOYA MAGALIE (FR)
MARGOLIS JONATHAN S (US)
MARGOLIS JONATHAN S (US)
Application Number:
PCT/US2012/039178
Publication Date:
April 25, 2013
Filing Date:
May 23, 2012
Export Citation:
Assignee:
AGRAQUEST INC A DELAWARE CORP (US)
GUILHABERT-GOYA MAGALIE (FR)
MARGOLIS JONATHAN S (US)
GUILHABERT-GOYA MAGALIE (FR)
MARGOLIS JONATHAN S (US)
International Classes:
A01N43/16; A01N43/713; A01N43/90; A01N63/50; A01P3/00; A61K31/70; A61P31/10; C07H17/08; C07K7/56
Domestic Patent References:
| WO2003013251A1 | 2003-02-20 |
Foreign References:
| FR2644038A1 | 1990-09-14 |
Other References:
CAITLIN REED ET AL: "Combination Polyene-Caspofungin Treatment of Rhino-Orbital-Cerebral Mucormycosis", CLINICAL INFECTIOUS DISEASES, vol. 47, no. 3, 1 August 2008 (2008-08-01), pages 364 - 371, XP055036778, ISSN: 1058-4838, DOI: 10.1086/589857
A. S. IBRAHIM ET AL: "Combination Therapy of Murine Mucormycosis or Aspergillosis with Iron Chelation, Polyenes, and Echinocandins", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 55, no. 4, 1 April 2011 (2011-04-01), pages 1768 - 1770, XP055036776, ISSN: 0066-4804, DOI: 10.1128/AAC.01577-10
MAGET-DANA R ET AL: "Iturins, a special class of pore-forming lipopeptides: biological and physicochemical properties", TOXICOLOGY, LIMERICK, IR, vol. 87, no. 1-3, 28 February 1994 (1994-02-28), pages 151 - 174, XP026042531, ISSN: 0300-483X, [retrieved on 19940228], DOI: 10.1016/0300-483X(94)90159-7
A. S. IBRAHIM ET AL: "Combination Therapy of Murine Mucormycosis or Aspergillosis with Iron Chelation, Polyenes, and Echinocandins", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 55, no. 4, 1 April 2011 (2011-04-01), pages 1768 - 1770, XP055036776, ISSN: 0066-4804, DOI: 10.1128/AAC.01577-10
MAGET-DANA R ET AL: "Iturins, a special class of pore-forming lipopeptides: biological and physicochemical properties", TOXICOLOGY, LIMERICK, IR, vol. 87, no. 1-3, 28 February 1994 (1994-02-28), pages 151 - 174, XP026042531, ISSN: 0300-483X, [retrieved on 19940228], DOI: 10.1016/0300-483X(94)90159-7
Attorney, Agent or Firm:
SAMONEK, Michelle, L. (INC.1540 Drew Avenu, Davis CA, US)
Download PDF: