Title:
SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/145302
Kind Code:
A3
Abstract:
The present invention relates to the synthesis of ent-progesterone and intermediates thereof.
Inventors:
CRAN JOHN W (US)
HAN YINGLIN (CN)
ZHANG FALIANG (CN)
HAN YINGLIN (CN)
ZHANG FALIANG (CN)
Application Number:
PCT/US2014/030040
Publication Date:
November 27, 2014
Filing Date:
March 15, 2014
Export Citation:
Assignee:
UNIV FLORIDA STATE RES FOUND (US)
PREVACUS INC (US)
PREVACUS INC (US)
International Classes:
B01J23/46; C07J75/00
Foreign References:
| US6369247B1 | 2002-04-09 |
Other References:
YANG, Z ET AL.: "Studies Directed toward Asymmetric Synthesis of Cardioactive Steroids via Anionic Polycyclization", ORGANIC LETTERS, vol. 4, no. 26, 2002, pages 4693 - 4696, XP055291777
MUSUMECI, D ET AL.: "The oxidation of delta2, delta2,4 and delta4,6 steroids with RuO4", STEROIDS, vol. 69, 2004, pages 173 - 179, Retrieved from the Internet [retrieved on 20140625]
HU , Y: "Studies Toward The Synthesis Of Dumsin. Doctoral Dissertation", 2008, OHIO STATE UNIVERSITY, pages FP - 229, XP055291778, Retrieved from the Internet [retrieved on 20140625]
AUCHUS, RJ ET AL.: "The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 409, 2003, pages 134 - 144, XP004479092
MUSUMECI, D ET AL.: "The oxidation of delta2, delta2,4 and delta4,6 steroids with RuO4", STEROIDS, vol. 69, 2004, pages 173 - 179, Retrieved from the Internet
HU , Y: "Studies Toward The Synthesis Of Dumsin. Doctoral Dissertation", 2008, OHIO STATE UNIVERSITY, pages FP - 229, XP055291778, Retrieved from the Internet
AUCHUS, RJ ET AL.: "The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 409, 2003, pages 134 - 144, XP004479092
Attorney, Agent or Firm:
MANSO, Peter, J. et al. (P.O. box 55874Boston, MA, US)
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