Title:
SYNTHESIS PROCESS FOR N-(ETHOXYCARBONYLPHENYL)-N'-METHYL-N'-PHENYLAMIDINE
Document Type and Number:
WIPO Patent Application WO/2019/233250
Kind Code:
A1
Abstract:
Disclosed is a synthesis process for N-(ethoxycarbonylphenyl)-N'-methyl-N' phenylamidine, comprising specific steps of: simultaneously adding three raw materials, i.e. ethyl p-aminobenzoate, trialkyl orthoformate and N-methylaniline, synthesizing N-(ethoxycarbonylphenyl)-N'-methyl-N'-phenylamidine in one step using petroleum ether as a solvent and glacial acetic acid as a catalyst. A water separator is provided on the reaction vessel, and the water separator is pre-passed with a freezing liquid. The solvent can be recycled after being refined. There is no need to use a toxic solvent in the post-treatment. The by-product methanol can be discharged out of the reaction system in time to increase the yield. The overall process flow has the advantages of low reaction temperature, short reaction time, low energy consumption, low contamination, and high yield.
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Inventors:
WU CHUNYE (CN)
ZHANG WENQING (CN)
ZHANG XIUXIU (CN)
WANG KE (CN)
GAI XUQIAO (CN)
ZHANG WENQING (CN)
ZHANG XIUXIU (CN)
WANG KE (CN)
GAI XUQIAO (CN)
Application Number:
PCT/CN2019/086868
Publication Date:
December 12, 2019
Filing Date:
May 14, 2019
Export Citation:
Assignee:
YANTAI XINXIU CHEMICAL TECH CO LTD (CN)
International Classes:
C07C257/12
Foreign References:
| CN108640857A | 2018-10-12 | |||
| CN102060734A | 2011-05-18 |
Other References:
LIU, QIONG ET AL.: "One Pot Synthesis of Ultraviolet Absorber N, N'-bis-aromaticformamidine", GUANGDONG CHEMICAL INDUSTRY, vol. 34, no. 165, 1 January 2007 (2007-01-01), pages 28-29 - 34, XP055667948
Attorney, Agent or Firm:
BEIJING DIRECTION STANDARD INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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