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Patent Searching and Data


Title:
SYSTEM FOR CORNEAL CROSS-LINKING AND CORRECTING VISION BY USING LED CONTACT LENS AND EYE DYE
Document Type and Number:
WIPO Patent Application WO/2021/049898
Kind Code:
A1
Abstract:
The present invention relates to a system for corneal cross-linking of injured corneas, treating keratoconus, or correcting vision, the system comprising: a hyaluronic acid-dye conjugate; and a contact lens including an LED light source. In the present invention, a dye is activated by receiving light irradiated from the LED light source of the contact lens so as to generate radicals, thereby generating a covalent bond between amino acid radicals of corneal collagen, and strengthening a collagen layer. In the present invention, the hyaluronic acid-dye conjugate, in which hyaluronic acid is bound to the dye, is used to improve penetration of the dye in the cornea, and the contact lens is used together with the hyaluronic acid-dye conjugate to further improve the penetration of the dye. In addition, the structure of the lens which presses the center of the cornea deforms the shape of the cornea, thereby having a vision correction effect.

Inventors:
HAHN SEI KWANG (KR)
SHIN SANG BAIE (KR)
MUN JONG HWAN (KR)
Application Number:
PCT/KR2020/012280
Publication Date:
March 18, 2021
Filing Date:
September 11, 2020
Export Citation:
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Assignee:
PHI BIOMED INC (KR)
POSTECH ACAD IND FOUND (KR)
International Classes:
A61F9/00; A61K9/00; A61K41/00; A61N5/06; A61P27/02; G02C7/04
Domestic Patent References:
WO2017145035A12017-08-31
Foreign References:
US20130211389A12013-08-15
US20150119356A12015-04-30
KR20140044300A2014-04-14
KR20140136922A2014-12-01
KR20150135335A2015-12-02
Other References:
HAN SEULGI, HWANG BYUNG WOO, JEON EUN YOUNG, JUNG DOOYUP, LEE GEON HUI, KEUM DO HEE, KIM KI SU, YUN SEOK HYUN, CHA HYUNG JOON, HAH: "Upconversion Nanoparticles/Hyaluronate–Rose Bengal Conjugate Complex for Noninvasive Photochemical Tissue Bonding", ACS NANO, AMERICAN CHEMICAL SOCIETY, vol. 11, no. 10, 24 October 2017 (2017-10-24), pages 9979 - 9988, XP055791445, ISSN: 1936-0851, DOI: 10.1021/acsnano.7b04153
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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