TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR

Title:

TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2021/032170

Kind Code:

A1

Abstract:

A tetracyclic compound as a Cdc7 inhibitor. Specifically disclosed is a compound represented by formula (I), an isomer thereof, or a pharmaceutically acceptable salt thereof. (I)

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Inventors:

LU LUN (CN)
LI GANG (CN)
HU LIHONG (CN)
DING CHARLES Z (CN)
CHEN SHUHUI (CN)

Application Number:

PCT/CN2020/110305

Publication Date:

February 25, 2021

Filing Date:

August 20, 2020

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Assignee:

MEDSHINE DISCOVERY INC (CN)

International Classes:

C07D493/14; A61K31/519; A61K31/5377; A61P35/00; C07D487/22; C07D491/22; C07D493/22

Domestic Patent References:

WO2007068728A2

2007-06-21

Foreign References:

CN102844320B	2016-03-23
CN1989131A	2007-06-27
US20090030196A1	2009-01-29
CN201910769786A	2019-08-20

Other References:

E. VANOTTI ET AL.: "Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potential Antitumor Agents. 1. Synthesis and Structure-Activity Relationships", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 51, no. 3, 14 February 2008 (2008-02-14), US, pages 487 - 501, XP002584693, ISSN: 0022-2623, DOI: 10.1021/JM700956R

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

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