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Title:
THERAPEUTIC AGENT FOR NOCTURNAL POLLAKIURIA
Document Type and Number:
WIPO Patent Application WO/2019/124507
Kind Code:
A1
Abstract:
[Problem] To provide a novel therapeutic agent for nocturnal pollakiuria. [Solution] A therapeutic agent for nocturnal pollakiuria which contains, as an active ingredient, (6S)-N-[4-({(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl}methyl)phenyl]-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxamide.

Inventors:
SEGAWA KATSUYA (JP)
KUROSE TAKAFUMI (JP)
Application Number:
PCT/JP2018/047038
Publication Date:
June 27, 2019
Filing Date:
December 20, 2018
Export Citation:
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Assignee:
KYORIN SEIYAKU KK (JP)
KISSEI PHARMACEUTICAL (JP)
International Classes:
A61K31/519; A61P13/10; A61P43/00
Domestic Patent References:
WO2009124167A12009-10-08
WO2004078163A22004-09-16
Foreign References:
JP2011510023A2011-03-31
Other References:
NITTI, V. ET AL.: "Results of a Randomized Phase III Trial of Mirabegron in Patients with Overactive Bladder", J UROL., vol. 189, no. 4, 1 April 2013 (2013-04-01), pages 1388 - 1395, XP055620059, ISBN: 0022-5347, DOI: 10.1016/j.juro.2012.10.017
NEUROUROL URODYN, vol. 23, 2004, pages 302 - 305
NEUROUROLOGY AND URODYNAMICS, vol. 34, no. 7, 2015, pages 685 - 692
BJU INTERNATIONAL, vol. 113, no. 6, 2014, pages 951 - 960
INTERNATIONAL JOURNAL OF UROLOGY, vol. 21, no. 10, 2014, pages 960 - 967
NEUROUROLOGY AND URODYNAMICS, vol. 32, no. 8, 2013, pages 1116 - 1122
JOURNAL OF UROLOGY, vol. 189, no. 4, 2013, pages 1388 - 1395
EUR. UROL. SUPPL., vol. 5, 2006, pages 3 - 11
SLEEP, vol. 14, 1991, pages 294 - 306
See also references of EP 3730141A4
Attorney, Agent or Firm:
MIZUNO, Katsufumi et al. (JP)
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