Title:
THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES TARGETING KINASES, SIRTUINS AND ONCOGENIC AGENTS FOR THE TREATMENT OF CANCERS
Document Type and Number:
WIPO Patent Application WO/2017/091837
Kind Code:
A3
Abstract:
A cannabis-based flavonoid pharmaceutical composition including any one or more selected from among the group of Cannflavin A, Cannflavin B. Cannflavin C, Chrysoeriol, Cosmosiin, Flavocannabiside and their derivatives selected from among the group of Geraldol, Rhamnetin, lsorhamnetin, Rhamnazin, or their synthases, for the prevention and treatment of certain cancers that can be treated by therapeutically targeting oncogenic factors including kinases, sirtuins, bromodomains, matrix metalloproteinases and histone acetylases. Some of the cancers that can be treated by use of cannabis flavonoids based on the inhibition of these therapeutic targets include but are not limited to brain, breast, colon, renal liver, lung, pancreatic, pigmented villonodular synovitis, prostate, leukemia, melanomam, tenosynovial giant cell tumor, as well as any other cancers that overexpress the oncogenic factors inhibited, by the cannabis flavonoids or their derivatives herein identified.
Inventors:
LOWE HENRY (JM)
TOYANG NGEH J (US)
TOYANG NGEH J (US)
Application Number:
PCT/US2016/066343
Publication Date:
October 12, 2017
Filing Date:
December 13, 2016
Export Citation:
Assignee:
FLAVOCURE BIOTECH LLC (US)
International Classes:
A61K31/352; C07D311/30
Foreign References:
| US20100222437A1 | 2010-09-02 | |||
| US9044390B1 | 2015-06-02 |
Attorney, Agent or Firm:
CRAIG, Royal, W. (US)
Download PDF:
Previous Patent: ENHANCEMENT OF CYTARABINE ACTIVITY BY INHIBITING CDK8/19
Next Patent: HAIR CUTTING DEVICE
Next Patent: HAIR CUTTING DEVICE