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Patent Searching and Data


Title:
Therapeutic anti-asthma agents containing selenium
Document Type and Number:
WIPO Patent Application WO1997026968
Kind Code:
A3
Abstract:
The description relates to a therapeutic agent which comprises as the active agent a compound given by the formula (1) and/or (1') and/or a pharmaceutically acceptable salt thereof. The agent of the invention exhibits great effectiveness in cases of both immediate and later asthmatic reactions, especially the latter. Owing to its low toxicity, the agent of the invention can safely be prescribed for human beings.

Inventors:
UCHIDA YOSHIYUKI (JP)
AKASHI AKIRA (JP)
Application Number:
PCT/DE1997/000135
Publication Date:
September 25, 1997
Filing Date:
January 27, 1997
Export Citation:
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Assignee:
NATTERMANN A & CIE (DE)
UCHIDA YOSHIYUKI (JP)
AKASHI AKIRA (JP)
International Classes:
A61K31/167; A61K31/195; A61K31/41; (IPC1-7): A61K31/165; A61K31/195; A61K31/41
Foreign References:
DE19506669A11996-08-29
US4778814A1988-10-18
EP0729756A11996-09-04
GB2238310A1991-05-29
Other References:
PATENT ABSTRACTS OF JAPAN vol. 096, no. 001 31 January 1996 (1996-01-31)
SCHEWE C ET AL: "Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione", BIOCHEM. PHARMACOL. (BCPCA6,00062952);94; VOL.48 (1); PP.65-74, HUMBOLDT UNIVERSITY BERLIN;INSTITUTE BIOCHEMISTRY; BERLIN; D-10115; GERMANY (DE), XP000654416
COTGREAVE I A ET AL: "The anti-inflammatory activity of Ebselen but not thiols in experimental alveolitis and bronchiolitis", AGENTS ACTIONS (AGACBH,00654299);88; VOL.24 (3-4); PP.313-19, KAROLINSKA INST.;DEP. TOXICOL.; STOCKHOLM; S-104 01; SWED. (SE), XP000654500
DATABASE WPI Derwent World Patents Index; AN 95-353429, XP002032846
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