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Patent Searching and Data


Title:
THERAPY FOR INTERSTITIAL CYSTITIS BY PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2021/085639
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel medical application using pluripotent stem cells in regenerative medicine. The present invention provides a cell formulation and pharmaceutical composition that are for amelioration and therapy for frequent urination and bladder pain caused by the inflammation of the bladder and that contain SSEA-3 positive pluripotent stem cells isolated from cultured mesenchymal cells or a mesenchymal tissue of a living organism. The cell formulation according to the present invention is considered to be based on a mechanism in which, for example, Muse cells are administered against interstitial cystitis having the abovementioned disorders to be successfully engrafted into affected bladder tissue, whereby the disorders are ameliorated and treated.

Inventors:
YAMAMOTO TOKUNORI (JP)
SHIMIZU SHINOBU (JP)
FURUTA AKIRA (JP)
DEZAWA MARI (JP)
KURODA YASUMASA (JP)
Application Number:
PCT/JP2020/040963
Publication Date:
May 06, 2021
Filing Date:
October 30, 2020
Export Citation:
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Assignee:
LIFE SCIENCE INST INC (JP)
NATIONAL UNIV CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP)
THE JIKEI UNIV (JP)
UNIV TOHOKU (JP)
International Classes:
A61K35/545; A61K35/28; A61P13/10; A61P43/00; C12N5/0775
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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