THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF

Title:

THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2019/056950

Kind Code:

A1

Abstract:

The present invention relates to a class of thienodiazepine derivatives and an application thereof in the preparation of a drug for the treatment of diseases associated with bromodomain and extra-terminal (BET) Bromodomain inhibitors. Specifically, the present invention relates to compounds represented by formulas (I) and (II), as well as pharmaceutically acceptable salts thereof.

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Inventors:

SHEN CHUNLI (CN)
WU CHENGDE (CN)
LIU YONG (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)

Application Number:

PCT/CN2018/104345

Publication Date:

March 28, 2019

Filing Date:

September 06, 2018

Export Citation:

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Assignee:

MEDSHINE DISCOVERY INC (CN)

International Classes:

C07D495/14; A61K31/55; A61K45/00; A61P35/00; A61P43/00; C07D243/06

Domestic Patent References:

WO2015018520A1

2015-02-12

Foreign References:

US5712274A	1998-01-27
CN101910182B	2013-07-17
CN201710867197A	2017-09-22

Other References: