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Title:
THROMBOPOIETIN MIMETICS
Document Type and Number:
WIPO Patent Application WO2002049413
Kind Code:
A3
Abstract:
Invented are non-peptide TPO mimetics. also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected substituted thiosemicarbazone derivative.

Inventors:
DUFFY KEVIN J (US)
LUENGO JUAN I (US)
MILLER STEPHEN G (US)
JENKINS JULIAN (US)
PRICE ALAN T (US)
SHAW ANTONY N (US)
Application Number:
PCT/US2001/050774
Publication Date:
January 23, 2003
Filing Date:
December 19, 2001
Export Citation:
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Assignee:
SMITHKLINE BEECHAM CORP (US)
LIGAND PHARMACEUTICALS (US)
DUFFY KEVIN J (US)
LUENGO JUAN I (US)
MILLER STEPHEN G (US)
JENKINS JULIAN (US)
PRICE ALAN T (US)
SHAW ANTONY N (US)
International Classes:
A61K31/04; A61K31/045; A61K31/05; A61K31/13; A61K31/131; A61K31/175; A61K31/192; A61K31/275; A61K31/325; C07D231/22; A61K31/352; A61K31/415; A61P7/00; A61P7/04; A61P43/00; C07C337/06; C07D307/91; (IPC1-7): A61P7/00; A61K35/16; A61K31/045; A61K31/05; A61K31/13; A61K31/131; A61K31/04; A61K35/28; A61K35/54
Domestic Patent References:
WO2001034585A12001-05-17
WO2000028987A12000-05-25
WO1999011262A11999-03-11
Other References:
See also references of EP 1349613A4
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