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Title:
ULTRAVIOLET STERILIZER
Document Type and Number:
WIPO Patent Application WO/2021/181236
Kind Code:
A1
Abstract:
The present invention is of a sterilization device. It features a sterilization chamber including at least one wall configured about a sterilization cavity, the cavity for accommodating at least one item to be sterilized in the sterilization chamber. The device includes at least one lamp configured for providing UV light for surface sterilization of the at least one item without heating the at least one item above about forty degrees centigrade, a power means for powering the device, and an opening element to open the device. In addition, the present invention is of a method of sterilizing at least one item.

Inventors:
NITZAN BOAZ (IL)
LIRAZ ELIANE (IL)
ENGLANDER JOSEPH (IL)
Application Number:
PCT/IB2021/051892
Publication Date:
September 16, 2021
Filing Date:
March 07, 2021
Export Citation:
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Assignee:
TUTTNAUER LTD (IL)
International Classes:
A61L2/10
Foreign References:
US20140341777A12014-11-20
US20090159813A12009-06-25
US20030155531A12003-08-21
US202062986809P2020-03-09
Attorney, Agent or Firm:
FRIEDMAN, Mark (IL)
Download PDF:
Claims:
WHAT IS CLAIMED IS:

1. A sterilization device comprising: a sterilization chamber comprising at least one wall configured about a sterilization cavity, the cavity for accommodating at least one item to be sterilized in the sterilization chamber; at least one lamp configured for providing UV light for surface sterilization of the at least one item without heating the at least one item above about forty degrees centigrade; a power means for powering the device; and an opening element to open the device.

2. The sterilization device of claim 1, further comprising at least one reflector, which is at least one of positioned on, integrally formed with and adjacent to the at least one wall, to reflect the UV light and direct the UV light to the at least one item.

3. The sterilization device of claim 2, wherein the at least one reflector comprises aluminum.

4. The sterilization device of claim 1, wherein the sterilization chamber is elliptically shaped.

5. The sterilization device of claim 4, wherein the sterilization chamber comprises a cylinder split longitudinally to two halves which are hingedly connected and which open to provide the opening of the device.

6. The sterilization device of claim 1, wherein the sterilization chamber comprises a recess configured to hold outside the sterilization chamber at least one section which is not to be sterilized of the at least one item whilst it is connected to at least one section of the at least one item held inside the cavity for sterilization.

7. The sterilization device of claim 6, wherein the at least one item comprises at least one section to undergo sterilization and at least one section which is not to be sterilized and wherein the at least one section which is not to be sterilized and is held outside the sterilization chamber is a non-detachable power cable.

8. The sterilization device of claim 1 wherein the device comprises a holding element configured to hold the at least one item parallel to the length of the at least one lamp.

9. The sterilization device of claim 8, wherein the holding element comprises at least one securing element, which is at least one of a hook for holding the at least one item in a vertical configuration and a UV transparent shelf for holding the at least one item in a horizontal configuration.

10. The sterilization device of claim 1, wherein during the sterilization cycle the sterilization chamber is a closed chamber and wherein the opening element is comprised of at least part of the at least one wall and wherein when the opening is closed the cavity is completely surrounded by the at least one wall.

11. The sterilization device of claim 8, wherein the at least one item is held such that it is spaced apart at a distance of from about 2.5 cm to about 6 cm from the at least one lamp.

12. The sterilization device of claim 2, wherein all the at least one wall comprises a reflector and the at least one lamp is one UV lamp.

13. The sterilization device of claim 1 , wherein the at least one lamp provides pulse

UV. 14. The sterilization device of claim 1, wherein the at least one lamp provides pulse UV with a wavelength of from about 180 nm to about 280 nm.

15. The sterilization device of claim 1, wherein the at least one lamp provides high power pulses for providing energy on the surface of the at least one item of from about 0.5 J/cm2 to about 5 J/cm2.

16. The sterilization device of claim 1, for surface sterilization of at least one of a vaginal probe, a rectal probe, a medical aesthetics instrument, a cosmetic instrument, a gynecological instrument and a dental instrument.

17. The sterilization device of claim 1, further comprising a motor to a least one of rotate the at least one item to be sterilized or translate the at least one item to be sterilized about the at least one lamp in the sterilization device.

18. The sterilization device of claim 1, further comprising a motor to a least one of rotate the at least one lamp or translate the at least one lamp about the at least one item to be sterilized in the sterilization device.

19. The sterilization device of claim 1, further comprising at least one control to control pulses of the UV light.

20. The sterilization device of claim 1, wherein the at least one lamp is disposed in at least one of a vertical or a horizontal configuration about the at least one wall.

21. The sterilization device of claim 1, wherein the at least one item is held in a bag constructed from ultraviolet transparent material.

22. The sterilization device of claim 1, wherein the device is calibrated for indicating completion of surface sterilization. 23. The sterilization device of claim 1, configured for sterilization of the at least one item in less than or about 90 seconds.

24. A sterilization system, comprising: the sterilization device of claim 1 ; and at least one container for holding the at least one item, the at least one container constructed from a UV transparent material.

25. A method of sterilizing at least one item, comprising: providing a device of claim 2; inserting an item for sterilization in the device such that at least one section of the at least one item is held in the cavity; closing the device; providing high power UV pulses to the at least one section; and sterilizing the surfaces of the at least one section of the at least one item held in the cavity.

26. The method of claim 25, wherein the sterilization chamber comprises a recess configured to hold outside the sterilization chamber at least one section, which is not to be sterilized of the at least one item whilst it is connected to at least one section of the at least one item held inside the cavity for sterilization, the method comprising: placing at least a part of the section of the item which is not to be sterilized in the recess.

27. The method of claim 25, wherein the sterilization chamber comprises a recess configured to hold outside the sterilization chamber at least one section of the at least one item which is not to be sterilized whilst it is connected to at least one section of the at least one item held inside the cavity for sterilization, wherein the at least one item comprises all sections for placement in the sterilization chamber, the method comprising: closing the recess with a closing element. 28. The method of claim 25, wherein providing high power UV pulses comprises providing energy on the surface of the at least one item of from about 0.5 J/cm2to about 5 J/cm2.

29. The method of claim 28, wherein providing high power UV pulses is for less than about 90 seconds.

Description:
Inventors: Boaz Nitzan, Eliane Liraz and Joseph Englander

Title: Ultraviolet Sterilizer

This application claims priority to U.S. Provisional Patent Application Ser. No. 62/986,809 filed on March 9, 2020 and incorporated by reference herein in entirety.

FIELD OF THE INVENTION

[0001] The present invention relates to a sterilizer. Moreover, the present invention is of a sterilizer that provides surface sterilization using pulsed ultraviolet (UV) light.

BACKGROUND OF THE INVENTION

[0002] It has been common practice to disinfect endo ultrasound probes, such as vaginal and rectal probes before their use. Some practitioners additionally or alternatively place a condom over the probe to prevent infection of a patient. However, recently regulations have changed, which now require the use of sterile probes. As such, endo ultrasound probes must undergo sterilization by a suitable sterili ation process. In view that the time between use of such probes from one patient to the next may be very short and may involve an interval of less than ten minutes there is a need for a very quick and effective way of sterilizing these instalments. Typically, probes can include electrical components for connection to an external diagnosis or treatment system. A suitable sterilization method must therefore be configured so that the electrical components are not affected by the sterilization conditions.

[0003] Available sterilization techniques use different technologies. High temperature is used in some systems, but this would not be suitable for endo ultrasound probes which may be damaged by the high temperature. In addition, the time for cooling to an optimal temperature suitable for insertion into a patient may be too long for this method to be feasible for very quick reuse of the probe. Some systems use chemicals, however chemical sterilization may be time consuming, may retain residue of the chemicals, which necessitates a washing phase and the chemicals may interact with the probe materials making them non ideal for use with such probes. Use of a vacuum system may not be adaptable to placement of a non- sterilizable section of a probe external to the sterilization system whilst the non- sterilizable section is still connected to the part of the probe in the vacuum chamber.

[0004] In some applications UV is effective in providing sterilization. However, this method causes an elevation of temperature, which may be sufficiently high to be damaging to the probes. The benefits of ultraviolet light for sterilization may be utilized with UV pulse technology. UV pulse sterilization can be used for surface sterilization and it is beneficial over continuous UV sterilization methods as it does not cause damaging high temperatures. In addition, pulse UV extends the life of the UV lamps and reduces the power requirements associated with continuous UV sterilization.

[0005] It would therefore be desirable to have a sterilizer device which provides very quick surface sterilization of probes and other medical and cosmetic instruments which are used in physical contact with patients for practical reuse of sterile probes and such instruments in successive patients. It would be beneficial if the sterilization technique was not detrimental to the instruments being sterilized, the users in which the instruments are to be used and the practitioners handling the instruments. It would be further desirable if the device was configured to provide sterilization of one section of a probe whilst a section of the probe which is not conducive to sterilization can be held externally and is not sterilized when still connected to the section being sterilized. It would further be advantageous to have a sterilizer which is compact for easy placement in a room with space restrictions, which is simple to use and affordable for surgery and clinic usage. The present invention provides such a device and method of use thereof. SUMMARY

[0006] The invention may have several aspects. One aspect is a sterilization device. The sterilization device may include a sterilization chamber. The sterilization chamber may feature at least one wall configured about a sterilization cavity, the cavity for accommodating at least one item to be sterilized in the sterilization chamber. The sterilization device may include at least one lamp configured for providing UV light for surface sterilization of the at least one item. The at least one lamp may be configured for sterilizing without heating the at least one item above about forty degrees centigrade. The device may include a power means for powering the device. The device may include an opening element to open the device. During the sterilization cycle the sterilization chamber is a closed chamber. The opening element may include at least part of the at least one wall, and wherein when the opening is closed the cavity is completely surrounded by the at least one wall.

[0007] In various embodiments of the sterilization device, the sterilizing device may include at least one reflector. The at least one reflector may be at least one of positioned on, integrally formed with and adjacent to the at least one wall, to reflect the UV light and direct the UV light to the at least one item. All the at least one walls may include a reflector and the at least one lamp may be one UV lamp. The sterilization chamber may be elliptically shaped. The sterilization chamber may include a recess configured to hold outside the sterilization chamber at least one section which is not to be sterilized of the at least one item whilst it is connected to at least one section of the at least one item held inside the cavity for sterilization. The device may include a holding element configured to hold the at least one item parallel to the length of the at least one lamp. The at least one lamp may be disposed in at least one of a vertical or a horizontal configuration about the at least one wall. The at least one item may be spaced apart at a distance of less than about 10 cm from the at least one lamp. The at least one reflector may be at an equidistance from the position of the at least one holding component as the at least one lamp is from the position of the at least one holding component. The at least one item may feature at least one section to undergo sterilization and at least one section which is not to be sterilized. The at least one section which is not to be sterilized and is held outside the sterilization chamber may be a non- detachable power cable. The section to undergo sterilization may include a section for contact with a patient and the section which is not to be sterilized may include at least one electric cable. The at least one section of the at least one item in the cavity may include the section to undergo sterilization and the section to undergo sterilization may feature a first section which is for contact with a patient and a second section which is not for contact with a patient. The at least one holding element may include a groove carved out of part of the at least one wall, the groove configured to hold a section of the at least one item, such that the section of the at least one item which is not to be sterilized is held outside the sterilization cavity. The holding element may include at least one securing element and wherein the at least one securing component may feature at least one of a hook for holding the at least one item in a vertical configuration and a UV transparent shelf for holding the at least one item in a horizontal configuration. The at least one wall of the sterilization device may include six walls configured as a cube about an internal cavity. The at least one reflector may be disposed on at least part of each of the six walls. The at least one reflector may include aluminum. The sterilization chamber may feature a cylinder. The at least one wall may include a plurality of walls configured as a cylinder about an internal cavity. The cylinder may feature a cylinder split longitudinally to two halves, which are hingedly connected and which open to provide the opening of the device. The at least one lamp may provide pulse UV. The at least one lamp may provide pulse UV with a wavelength of from about 180 nm to about 280 nm. The at least one lamp may provide pulse UV with a wavelength of from about 250 nm to about 280 nm. The at least one lamp may provide high power pulses for providing energy on the surface of that least one item of from about 0.5 J/cm to about 5 J/cm . The at least one item may be held in a bag constructed from ultraviolet transparent material. The sterilization device may be for surface sterilization of the at least one item. The device may be calibrated for indicating completion of surface sterilization. The device may be calibrated with at least one indicator, such as but not limited to a biological indicator for indicating completion of surface sterilization. The at least one item may be one item and the device may be for sterilization of one item. The device may be for surface sterilization of at least one of a vaginal probe, a rectal probe, a medical aesthetics instrument, a cosmetic instrument, a gynecological instrument and a dental instrument. The device may be configured for sterilization of the at least one item in less than or about 90 seconds. The device may be for sterilization of the at least one item in less than or about 30 seconds. The device may also feature a motor to rotate the at least one item to be sterilized or translate the at least one item to be sterilized about the at least one lamp in the sterilization device. The device may feature a motor to a least one of rotate the at least one lamp or translate the at least one lamp about the at least one item to be sterilized in the sterilization device. The at least one lamp may be one lamp. The at least one lamp may be two lamps. The at least one holding component for holding the at least one item parallel to the length of the at least one lamp holds the at least one item such that it is spaced apart at a distance of from about 2.5 cm to about 6 cm from the at least one lamp. The device may include a frame to hold the at least one wall configured about a sterilization cavity. The device may include at least one control to control pulses of the UV light.

[0008] A further aspect is a sterilization system. The sterilization system may include the sterilization device as described herein. The sterilization system may include at least one container for holding the at least one item, the at least one container constructed from a UV transparent material. The at least one lamp may provide pulse UV with a wavelength of from about 180 nm to about 280 nm.

[0009] An additional aspect is a method of sterilizing at least one item. The method includes providing a sterilization device of the present invention as described herein. The method includes inserting an item for sterilization in the device. The method includes closing the device. The method includes providing high power UV pulses to at least one section of the at least one item and sterilizing the surfaces of the at least one section of the at least one item held in the cavity.

[0010] In various embodiments of the method of sterilizing at least one item, the at least one item is one item. The sterilization chamber may include a holding component. The holding component may feature a recess, which may be carved out of part of the at least one wall. The recess may be configured to hold outside the sterilization chamber at least one section, which is not to be sterilized of the at least one item whilst it is connected to at least one section of the at least one item held inside the cavity for sterilization, the method including placing at least a part of the section of the item which is not to be sterilized in the recess. The method may feature closing the recess with a closing element when the at least one item includes all sections for placement in the sterilization chamber. The device may further include at least one securing component, the at least one securing component featuring a hook and wherein the method includes hanging the item vertically by the hook. The method may include placing the at least one item in a bag constructed from UV transparent material before inserting the item in the device. In the method, providing high power UV pulses may include providing energy on the surface of the at least one item of from about 0.5 J/cm to about 5 J/cm . The method may include providing high power UV pulses for less than about 90 seconds. The method may include determining completion of the sterilizing process with a detector measuring UV light intensity.

RRTF.F PRSCRIPTION OF THE DRAWINGS

[0011] The various features of the invention will best be appreciated by simultaneous reference to the description which follows and the accompanying drawings, which are not drawn to scale and in which:

[0012] FIGs la and lb show a schematic view of an exemplary sterilizer device according to an aspect of the present invention; [0013] FIGs 2a-2c show schematic views of non-limiting exemplary configurations of a sterilization device according to aspects of the present invention;

[0014] FIG. 3 shows a schematic view of an exemplary sterilizer with two UV lamps according to an aspect of the present invention;

[0015] FIG. 4 shows a schematic view of an exemplary sterilizer with a horizontally positioned UV lamp according to an aspect of the present invention;

[0016] FIGs 5a-5c show schematic views of exemplary reflector arrangements according to aspects of the present invention;

[0017] FIG. 6 shows a schematic view of an exemplary arrangement of an exemplary sterilization device according to an aspect of the present invention;

[0018] FIGs 7a-7d show schematic views of exemplary sterilization devices according to aspects of the present invention;

[0019] FIG. 8 shows a schematic view of an exemplary item to be sterilized in an exemplary sterilization device according to an aspect of the present invention;

[0020] FIGs 9a-9c show schematic views of an exemplary item to be sterilized held in an exemplary sterilization device according to aspects of the present invention;

[0021] FIGs 10a- lOd show schematic views of exemplary configurations of an exemplary sterilization device according to aspects of the present invention;

[0022] FIG. 11 shows a schematic view of an exemplary control of an exemplary sterilization device according to an aspect of the present invention;

[0023] FIG. 12 shows a schematic view of an exemplary sterilizer system according to an aspect of the present invention; and

[0024] FIG. 13 shows a flow chart of an exemplary method of use of an exemplary sterilizer according to an aspect of the present invention. DETAILED DESCRIPTION

[0025] In one aspect the present invention is of a sterilization device. The sterilization device provides surface sterilization using UV pulses. In a further aspect, the present invention provides a system featuring a sterilization device of the present invention and at least one container constructed from a UV transparent material for holding an item to be sterilized. Furthermore, the present invention provides a method of surface sterilization.

[0026] The device, system and method of the present invention have many advantages. The device, system and method provide a user with a means of sterilizing the surface of a wide variety of instruments including probes for use in internal cavities, such as ultrasound probes for use vaginally and rectally and including instruments used in medical aesthetic treatments. The device, system and method may provide a user with a means for sterilizing a wide variety of probes with smooth surfaces. The device and system facilitate very quick surface sterilization. The sterilization may take as little as tens of seconds, thus allowing very quick reuse of the instrument. The device and system feature a sterilization technique, which is safe and does not lead to high temperatures. The UVC pulses may cause slight heating of the items being sterilized, the elevated temperature less than about forty degrees centigrade. This is significantly less than temperatures of above about one hundred degrees centigrade resulting from non-pulsed continuous UV treatment. The device of the present invention can be used to sterilize an item, which includes at least one non detachable section which should not be exposed to the sterilization conditions, such as but not limited to a section including an electric cable. The device, system and method of use thereof are designed to provide sterilization of an item which includes a plurality of connected sections, such that a section of the item which is not recommended for exposure to the sterilization conditions can be held external to a sterilization chamber during the sterilization cycle, whilst remaining connected to the sections of the item being sterilized in the sterilization cavity. The device of the present invention is also configured so that it is compact, the space saving beneficial to surgeries with limited room.

[0027] As used herein the term ‘sterilization chamber’ may include, but is not limited to a compartment or suitable cavity where sterilization may be carried out.

[0028] As used herein the term ‘connection’ may include, but is not limited to direct and indirect attachment.

[0029] As used herein the term ‘inlet’ may include, but is not limited to a means of entry. The term may include any suitable means of entry, such as, but not limited to vents, ducts, pipes, flues and openings.

[0030] As used herein the term ‘outlet’ may include, but is not limited to a means of exit. The term may include an opening or passage configured for letting something out. The term may include vents, pipes, ducts and exits for expelling something.

[0031] As used herein the term ‘channel’ may include, but is not limited to a passage or a structure, which provides a passage or pathway for a material, such as a gas, vapor or liquid to flow along. The term may include a channel made from a material resistant to the material it is carrying. The term may include a channel for a separated passage of a material.

[0032] As used herein the term ‘sterilization device’ may include, but is not limited to a sterilizer, which features a sterilization chamber or any suitable cavity for placement of an item to be sterilized. The sterilizer may provide the sterilization chamber or suitable cavity with sterilization conditions, materials, and other means for facilitating a sterilization process and sterilization of items in the sterilization chamber.

[0033] As used herein the term ‘sterilization’ may include, but is not limited to elimination, killing, removal or deactivation of biological agents, such as, but not limited to microorganisms, pathogens, bacteria, viruses, fungi, spore forms and prions from a specified region. Sterilization may be performed using a sterilization process and may run for longer than is required to provide a sterility assurance level. The term may include a process providing a sterility assurance level of at least 10 6 .

[0034] As used herein the term ‘disinfection’ may include, but is not limited to a process to destroy microorganisms on a specified region. The term includes a method, which is less effective than sterilization at killing microorganisms and may not kill all microorganisms on a specified area, such as resistant bacterial spores.

[0035] As used herein the term ‘sterilization cycle’ may include, but is not limited to at least one stage of a sterilization procedure. The sterilization cycle may include all the stages of the sterilization procedure or only at least one stage.

[0036] As used herein the term ‘medical aesthetic treatments’ may include, but is not limited to cosmetic treatments, dermatological treatments, epilation, treatment of acne, treatment of wrinkles, anti-aging treatment, tattooing, removal of tattoos, laser treatments, skin lightening, cellulite treatment, treatment of veins, scar treatment, pigmentation treatment, rosacea and gynecological treatments.

[0037] As used herein the terms ‘a’ and ‘an’ may mean ‘one’ or ‘more than one’.

[0038] As used herein the terms ‘comprising’, ‘including’, ‘containing’, ‘featuring’,

‘having’ and any forms of the terms thereof are inclusive and open ended and do not exclude additional elements or method steps, which are not recited.

[0039] The principles and operation of a system and device, such as a sterilizer, as well as methods of use thereof according to the present invention may be better understood with reference to the figures. The figures show non-limiting aspects of the present invention.

[0040] The Sterilization Device [0041] Figure la shows a schematic view of an exemplary sterilizer 10 according to an aspect of the present invention. The sterilizer 10 is configured as a sterilizer for providing surface sterilization of an item using pulses of ultraviolet light.

[0042] The sterilization device 10 may feature a cavity or space 12 within the device which is configured as a sterilization chamber 14. The sterilization chamber 14 may be of any suitable shape for holding and sterilizing at least one item 22 as shown schematically in Figure lb. The shape may be configured according to the item 22 to be sterilized in the sterilization device 10. The sterilization chamber 14 may be formed from at least one wall 16. The at least one wall 16 may be configured about the sterilization cavity 12, the cavity 12 for accommodating the at least one item 22 to be sterilized. The number of walls 16 may depend on the shape of the chamber 14 and/or the shape of the device 10. The wall/s of the device may be elliptical to provide an elliptical shaped sterilization chamber. Figures 2a, 2b and 2c show schematic views of non-limiting exemplary shapes of a sterilization device 10 of the present invention. In one non-limiting example shown in Figure 2a, the sterilization chamber 14 may have a tubular like configuration. In such an example, the device may feature a top circular wall 16a, a bottom circular wall 16b and an encircling side wall 16c about a sterilization cavity. In an alternative non-limiting example shown schematically in Figure 2b the device 10 may be spherical and may correspondingly include one wall 16a. In a further non-limiting example shown schematically in Figure 2c the device may have a box shape and may include six walls 16, a top wall 16a, a bottom wall 16b, a front wall 16d, a back wall 16e, a left side wall 16f and a right side wall 16g. The walls 16 of the device 10 may be made from any suitable material, which withstands and is inert to the sterilization conditions.

[0043] Referring back to Figure la, in some embodiments, the sterilization device 10 may include a frame 18. The frame 18 may be configured to hold the sterilization chamber 14. The frame 18 may provide an external skeleton for the device 10. The frame 18 may be configured to provide a stable configuration for resting the device 10 on a surface, such as but not limited to a suitable work surface. The frame 18 may be of any suitable shape and may include any suitable number of faces. The frame 18 may have a different shape than the sterilization chamber 14. The frame may include a base 19.

[0044] The sterilization device may include at least one UV lamp 20 for providing sterilization with UV light. The at least one UV lamp 20 may be configured for providing UV light for surface sterilization of at least one item. The at least one UV lamp 20 may be configured for providing pulses of UV light. The at least one UV lamp 20 may be configured for providing sterilization of at least one item without heating the at least one item above about forty degrees. The at least one UV lamp 20 may be configured for providing sterilization of at least item without heating the at least one item above about thirty degrees. The UV lamp 20 may be any suitable lamp configured to provide UVC light. The UV lamp may be a lamp, which can provide UV light in a wavelength of from about 180 nm to about 400 nm. The UV lamp 20 may be configured to optimize UVC light provision in a wavelength of from about 180 nm to about 280 nm. In some embodiments, the UV lamp 20 may be configured to optimize provision of UV light in a wavelength of from about 200 nm to about 270 nm. In one embodiment the UV lamp 20 is configured to provide an optimal amount of light of about 254 nm for aximal UV sterilization effect. UV light of from about 180 nm to about 200 nm may facilitate formation of ozone. The ozone may have a sterilization effect in addition to the UV radiation sterilization effect. The device 10 may include an ozone trap for trapping any residual ozone after completion of the sterilization. The UV lamp 20 may be a xenon gas lamp for optimizing the UVC yield, but other lamps may be used. The UV lamp 20 may be configured to give high peak power pulses. In one non-limiting example the UV lamp provides energy intensity of a discreet pulse so that the measured surface energy on an item being sterilized by pulses from the lamp is from about 0.5 J/cm to about 5 J/cm . The flashes/pulses may have any suitable frequency. In one non-limiting example the flashes have a frequency of from about 1 Hz to about 3 Hz. Any suitable number of flashes may be used. The number of flashes may range from about 3 to about 30. The number of flashes may be dependent on the distance of the at least one item to be sterilized from the UV lamp. In one non-limiting example, the distance may be about 3 cm and the number of flashes may be up to about 5. In an alternative non limiting example, the distance may be about 6 cm and the number of flashes for sterilization may be up to about 20. The flashes may be timed and equally spaced during a treatment time. The treatment time may be calculated according to parameters such as, but not limited to the number of pulses, the power of the UV lamp, the wavelength of the UV light, the number of UV lamps, the number of reflectors and the distance the item to be sterilized is placed from the UV lamp/s. The treatment time can be adjusted by adjusting these parameters. In some embodiments, the treatment time may be at least about 3 seconds or more. In one non-limiting example the device is configured for a treatment time of about 30 seconds. The device may be configured for sterilization of at least one item in less than or about 90 seconds.

[0045] In one embodiment the device includes one UV lamp 20 as shown schematically in Figure la. In an embodiment of the device 10 which includes a plurality of UV lamps, the device 10 may provide more uniform exposure of the at least one item 22 to UV light and the sterilization process may be faster. The number of UV lamps 20 used may depend on the length of the item 22 to be sterilized. In an example wherein the UV lamp 20 is shorter than the item 22 to be sterilized, a plurality of UV lamps 20, which may be joined bottom to top may provide the needed length for optimal sterilization. The power requirements for a multi UV lamp device may be higher than for a single UV lamp device.

[0046] The at least one UV lamp 20 may be placed against any suitable wall 16 of the device 10. In an embodiment where there is only one UV lamp 20, the UV lamp may be placed adjacent to an inner wall 16 of the sterilization chamber 14. In an embodiment where the device 10 includes two UV lamps 20 as shown schematically in Figure 3, the first lamp 20a may be positioned to face a first side, such as for example a front side of the at least one inserted item 22 and the second lamp 20b may be placed adjacent to a wall 16 or part of the wall which faces the opposite side of the at least one item 22, such as the backside of the length of the at least one item 22 when the at least one item is inserted in the sterilization chamber 14. In some embodiments the UV lamp 20 may be placed spaced apart from the wall 16 of the device 10. In an embodiment wherein the UV lamp 20 is spaced apart from the wall, a reflector 30 on that wall may provide more light to the at least one item 22 than an example wherein the UV lamp 20 is positioned flush against the wall. The UV lamp 20 may be spaced apart from the walls 16 of the device in order not to cause any damage by heat generated from the UV lamp 20. In an embodiment the UV lamp 20 may be attached to a motor to rotate or translate the UV lamp 20. The UV lamp 20 may rotate around the at least one item 22 being sterilized in the sterilization device. Such an embodiment may be advantageous for facilitating uniform sterilization of all the surface of the at least one item 22 when the device includes only one UV lamp 20. The UV lamp 20 may translate in any suitable way to provide uniform exposure of the pulses to the at least one item 22 being sterilized.

[0047] The UV lamp may be of any suitable shape and dimensions, including but not limited to a linear or a spiral bulb. The at least one UV lamp 20 may be of any suitable length 32. In some embodiments, the length 32 of the UV lamp 20 extends vertically from the top 16a of the sterilization chamber 14 to the bottom 16b of the sterilization chamber 14 as shown schematically in Figure la. In some embodiments, the length 32 of the UV lamp 20 may be positioned to extend horizontally along at least one wall of the device as shown schematically in Figure 4. In a non-limiting example of a rectangular sterilization device the UV lamp 20 may extend horizontally adjacent to the back wall 16e, extending from the left side wall 16f until the right side wall 16g. Typically, the length 32 of the UV lamp 20 may be the same or longer than the at least one item 22 or the part of the at least one item, which is to be sterilized. The length 32 of the UV lamp 20 may be defined for optimal sterilization of the at least one item 22. A UV lamp 20 which is shorter than the section or all of the at least one item 22 to be sterilized may not provide sufficient UV radiation to parts of the surface of the at least one item 22. Non limiting examples of suitable lengths of UV lamp which can be used in the present invention range from about 15 cm to about 45 cm. In some embodiments, shorter or longer UV lamps are used. The UV lamp 20 may be configured for electrical connection to a power source of the device 10.

[0048] The sterilization device 10 may include at least one reflector 30. The reflector 30 may be configured for reflecting the UV light from the at least one UV lamp 20 into the sterilization chamber 14 for maximizing the UV light exposure and UV light received on the at least one item 22 being sterilized. The reflector may be a mirror or may be configured to act as a mirror. The reflector/s 30 may be placed to provide optimal reflection and substantially no shadow on the at least one item 22 to be sterilized. The device may include any suitable number of reflectors 30. A reflector 30 may be sized to about the dimensions of a wall of the device 30. In one non-limiting embodiment, a wall 16 of the device 10 may include a plurality of reflectors 30 of smaller size. In one non-limiting example one wall of the sterilization device includes a reflector 30. In an additional non-limiting example, all the walls 16 of the sterilization chamber 14 may include a reflector 30. Non limiting examples of a suitable reflector include aluminum and silver.

[0049] The reflector 30 may be an attachable reflector which is attachable to the sterilization device 10. A detachable/attachable reflector 30 may enable use of at least one reflector 30 in the sterilization device 10, wherein the reflector 30 and the number of reflectors used are configured according to the properties of the UV lamp and the chamber 14. An attachable reflector 30 may include attachment means 34 on the reflector 30, which can be attached to and detached from corresponding attachment means of the sterilizer device 10. Figure 5a shows two different schematic views of a non-limiting example of a detachable reflector 30 attached to a wall 16 of the sterilization chamber with attachment means 34. The reflector may be adjacent to the wall 16. In an alternative embodiment, the reflector 30 may be permanently attached to the device. In one embodiment, the reflector 30 may be a coating or a layer attached to at least one of the walls 16 of the sterilization chamber 14 as shown schematically in Figure 5b. In one embodiment, the walls 16 of the sterilization chamber 14 may be constmcted from a material which functions as a reflector 30 as shown schematically in Figure 5c. In such an embodiment the reflector 30 is integrally formed with the at least one wall.

[0050] The sterilization chamber 14 may be of any suitable size. The size may be determined according to the end use of the device 10. The device may be a modular device, which may provide a device and sterilization chamber 14 which can change size. The sterilization chamber 14 may be constructed with minimal dimensions for holding at least one item 22 for sterilization. In some embodiments, the sterilization chamber 14 may be sized for holding one item 22 to be sterilized. The sterilization chamber 14 may be sized according to the optimal distance 40 from the item 22 to be sterilized to the at least one UV lamp 20 providing UV light. The sterilization chamber 14 may be sized according to the optimal distance 40 from the item 22 to be sterilized to the UV lamp 20, plus the distance 42 from at least one reflector wall 30 to the item 22 to be sterilized as shown schematically in Figure 6. In one non-limiting example, the distance 40 from the at least one UV lamp 20 to the item 22 to be sterilized may be up to about 10 cm. In a further non-limiting example, the distance 40 from the at least one UV lamp 20 to the item 22 to be sterilized may be up to about 6 cm. In a still further non-limiting example, the distance 40 from the at least one UV lamp 20 to the item 22 to be sterilized may be up to about 3 cm. In one non-limiting example the item 22 is held such that it is spaced apart at a distance of from about 2.5 cm to about 6 cm from the at least one UV lamp 20. Larger and smaller distances between the item 22 and UV lamp 20 are possible in the device of the present invention. The distance of the UV lamp 20 from the at least one item 22 is also determined in order that the at least one item 22 is sufficiently spaced apart from the UV lamp 20 so as not to be affected by heat from the at least one UV lamp 20. In some embodiments, the diameter of the cavity 12 may be about twice the distance from the item 22 to be sterilized to the UV lamp 20. In such an embodiment, the at least one item 22 may be placed in the sterilization cavity 12 at a substantially midpoint 44 of the sterilization chamber 14. [0051] In a sterilization device where the device 10 is configured for vertical holding of the at least one item 22 to be sterilized, the length 46 of the sterilization chamber may be sized according to the length 47 of the at least one item 22 or the part of the at least one item 22 to be sterilized as shown schematically in Figure 7a. The length 46 of the sterilization chamber 14 may be a suitable length to allow the at least one item 22 to be sterilized to hang vertically in a fully extended and unfolded configuration. In an example wherein the item 22 is a vaginal or rectal probe, the probe may be substantially rigid and may hang fully extended. There may be a gap 48 between the top extremity 50 of the at least one item 22 to be sterilized or the part of the at least one item 22 to be sterilized and the top wall 16a of the sterilization chamber 14 and a gap 52 between the bottom extremity 54 of the at least one item 22 to be sterilized and the bottom wall 16b of the sterilization chamber 14. Such an arrangement may be suitable for an item or items being sterilized wherein the entire instrument or a disconnected part of an instrument is placed in the sterilization chamber for sterilization. In some embodiments as shown schematically in Figure 7b, there may only be a gap 52 between the bottom extremity 54 of the at least one item 22 and the bottom wall and there may be no gap between the top extremity 50 of the at least one item 22 and the top wall 16a of the sterilization chamber. Such an arrangement without a top gap 48 may be suitable for sterilization of an item 22 which includes a section that protrudes from the top wall 16a.

[0052] In a sterilization device where the device is configured for holding the length 47 of the at least one item 22 to be sterilized in a horizontal configuration, the width 60 of the sterilization chamber 14 may be sized according to the length 47 of the at least one item to be sterilized as shown schematically in Figure 7c. In such an embodiment, the width 60 of the sterilization chamber 14 may be of suitable dimensions to allow the at least one item 22 to be sterilized to be placed horizontally in a fully extended and unfolded configuration. In an embodiment wherein a section 74 of one extremity 50 of the at least one item 22 is protruding out of a first side wall 16, the sterilization chamber 14 may not include a gap between the first extremity of the at least one item 22 and the first side wall, but may include a gap 64 between the second extremity 54 of the at least one item 22 to be sterilized and the respective adjacent side wall 16 of the sterilization chamber 14. In an embodiment, wherein all sections of the item to be sterilized are completely immersed in the sterilization chamber 14 as shown schematically in Figure 7d, there may be a gap 62 between a first extremity 50 of the at least one item to be sterilized and the adjacent side wall 16 of the sterilization chamber and a gap 64 between the second extremity 54 of the at least one item 22 to be sterilized and the respective adjacent side wall 16 of the sterilization chamber 14.

[0053] In one non-limiting example the at least one item 22 to be sterilized may be a transvaginal probe or transducer. The probe may have any suitable dimensions. In one non-limiting example the section of the probe to be sterilized has a length 47 of from about 15 cm to about 40 cm. As described hereinabove the length 46 of the cavity 12 of the sterilization device 10 may be longer than the length 47 of the at least one item 22 in order that there is a gap between at least the lower extremity of the at least one item and the device walls, for providing sterilization of the extremity of the at least one item. In such an example the UV lamp 20 may be at least the length of the part of the probe to be sterilized and may be at least about 15 cm.

[0054] Referring to Figure 8, which shows a schematic view of an exemplary item to be sterilized in a sterilization device according to an aspect of the present invention, wherein the at least one item 22 to be sterilized may include a plurality of sections. At least one section 68 of the item 22 may be for contact with a patient, such as internal contact with a patient and may be configured for sterilization. One non-limiting example of the at least one section for contact with the patient is the wand section 68 of a transducer 22, which can be inserted internally into the patient through a suitable cavity, such as the vagina or rectum. The at least one item 22 may include at least one section which does not need to be sterilized 70 as this section may not be configured for contact with a patient. However, this section 70 may be exposed to the sterilization conditions of the device of the present invention without any detrimental effect on this section 70. A non-limiting example of this type of section 70 is a handle section, which is held by the person conducting the examination with the probe 22. The item 22 may include at least one section 74 which is not conducive to sterilization. The at least one item 22 to be sterilized may be connected to a section or component/s 74, which may be non- detachable and for which sterilization is not recommended. When the at least one item 22 is used, this section 74 may not be configured for direct contact with a patient and therefore may not need to be sterilized. In one non-limiting example, the section 74, which is not for sterilization may be an electric cable. The electric cable may be a non-detachable power cable. The electric cable may be for insertion into an attachment element for attachment to a unit, such as for example an ultrasound device. In one non-limiting example, one extremity 50 of the at least one item 22 to be sterilized may include a section 74 with electrical connections, which may be sensitive to sterilization conditions and for which exposure to the sterilization conditions must be prevented. In one non-limiting example the at least one item 22 may include a section for connection 76 between the handle or other non-contact with patient section 70 and the section which must not be sterilized 74. The connection section 76 may be configured to withstand exposure to the sterilization conditions, such as the UV pulses of the sterilizer.

[0055] The device 10 of the present invention as shown schematically in Figure lb includes a component/means 80 for positioning and/or holding of the at least one item 22, such that the at least one section to be sterilized is held in the sterilization chamber cavity and a section of the item, which is not conducive to be sterilized is held outside the sterilization chamber. The holding element 80 may hold the at least one item 22 parallel to the length of the at least one lamp. The component 80 may be configured to hold a section 74 of an extremity of the item 22 to be sterilized so that it is outside and not within the sterilization chamber 14. The means 80 may include a cavity or a groove, such as a recess, which may be carved out of a suitable wall of the device and may be sized and shaped to receive and hold a part 74 of the item 22, which is not to undergo sterilization. The recess may be configured to hold outside the sterilization chamber at least one section which is not to be sterilized of the at least one item whilst it is connected to the at least one section of the at least one item held inside the cavity for sterilization. In some embodiments, the holding component may also be configured to accommodate a connection section 76 of the at least one item 22, in order that there is a further distance between the section which cannot withstand the sterilization conditions 74 and the sterilization cavity 12. In some embodiments the holding component 80 may be configured to hold part of the extremity of the handle section 70 of the at least one item 22. In some embodiments, such as a sterilization device which opens out longitudinally to provide two connected parts 82, 84 of a sterilization chamber 14 as shown schematically in Figure lb, both parts of the device 82 and 84 may feature a portion of the holding component 80 configured to hold the section 74 of the item outside the sterilization chamber 14 and facilitate that when the two parts 82, 84 of the device are brought together and connected so that the sterilization chamber 14 is closed, the sterilization chamber 14 is sealed and the section 74 of the item protmding out of the sterilization chamber does not prevent or affect the sealing of the sterilization chamber 14. The sterilization device may include components to aid in sealing the sterilization chamber 14, such as but not limited to a seal, which may be a rubber seal. The sealing component may facilitate optimizing the UV light within the sterilization chamber 14 and preventing the UV light from scattering outside the sterilization chamber 14. The sealing component may be positioned suitably about the holding component 80. A sealing component may additionally be positioned about the two parts 82, 84 of the device or any door or other suitable opening of the sterilization device 10. A part of the section not to be sterilized 74 may protrude out of the sterilization device. In one non-limiting example wherein the sterilization device includes a frame 18, the section 74 which is not contained in the sterilization cavity 12 may stick out of the top wall of the frame. In an embodiment wherein the at least one item 22 does not include a section 74 which is to be held external to the sterilization chamber, a plug sized to fit the holding component 80 may be inserted in the holding component 80 in order that the sterilization chamber 14 is sealed when the opening of the device is closed. The device may include a component which is built in and can be employed to seal at least part of the holding component 80 in order that the sterilization chamber is substantially sealed during sterilization when the holding component 80 does not hold a part of the item to be sterilized 22. The device is configured so that the sterilization chamber is a closed chamber during the sterilization cycle.

[0056] The holding component 80 for accommodating a section of the item 74 which is not to be sterilized as described hereinabove may be configured and sized to firmly hold the at least one item 22, with the section/s for sterilization correctly positioned within the chamber 14 and the section/s not conducive to sterili ation held external to the chamber. In some embodiments, the holding component 80 is not configured to securely hold the item to be sterilized. The sterilization device 10 may include at least one securing component for holding 100 or aiding in holding the at least one item 22 to be sterilized in the cavity 12 of the device 10. Figure 9a shows schematically an exemplary securing component 100 arranged in the sterilization device of the present invention. The at least one securing component 100 may be one securing component, or a plurality of securing components. In an embodiment, the means for accommodating a section of the item 80 may include at least one securing component 100. In some embodiments the at least one securing component 100 may be attached at any suitable position in the sterilization device. In an embodiment of a plurality of securing components 100, the plurality of securing components 100 may be spaced apart. The positioning of the securing components 100 may depend on the position of the holding component 80. The position of the holding component 80 may be fixed and as such the securing components 100 may be placed and spaced for holding an item 22 to be sterilized which is placed in the holding component 80. In one non-limiting example the at least one securing component 100 is a hook to which the at least one item can be attached. An additional non-limiting example of a securing component 100 is a chuck as shown schematically in Figure 9a, which clamps the extremity of the item 22. Other non-limiting examples of securing components 100 include at least one link, tie, rail, press studs, ball and loop attachment means, clip, clamp, clasp, teeth, peg, magnet and socket. In one embodiment, the at least one securing component 100 may be attached to a rotating means 102 for rotating the securing component 100. Rotation of the securing component 100 may facilitate rotation of the attached at least one item 22 to be sterilized. The means for rotating 102 the at least one item may include a motor. The rotational means 102 may facilitate more uniform exposure of the at least one item 22 to be sterilized to the UV light from the at least one UV lamp 20. The speed of the rotational means 102 may be set according to the frequency of the UV pulses. The rotational means 102 may be configured to rotate and/or translate the item 22 being sterilized so that all the surfaces of the at least one item 22 being sterilized are exposed to the same conditions of the light source. Rotational means 102 may be advantageous when the sterilization device includes one UV lamp 20.

[0057] In one non-limiting embodiment, the distance of the at least one item held in the holding component 80 from the UV lamp may be changeable. The distance may be changed by moving the UV lamp. The movement may be automatic or manual.

[0058] As shown in Figure 9a the at least one securing component 100 may be positioned on the roof 16a of the sterilization chamber 14, or on the frame connected to the top wall of the sterilization chamber 14. An at least one securing component 100, which is attached to the top wall of the chamber 14 or frame provides a way of holding the at least one item in a vertical configuration, so that the length of the at least one item 22 extends from the top of the chamber 16a towards the bottom wall 16b or bottom part of the chamber 14. The at least one securing component 100 may be attached so that it is near the midline 44 of the sterilization chamber 14. The at least one securing component 100 for holding the at least one item to be sterilized in a vertical configuration may be used when the at least one UV lamp 20 is attached to the sterilization device such that the length of the UV lamp is in a similar vertical configuration. The at least one securing component 100 may be positioned in the sterilization device so that an at least one item 22 attached to the at least one securing component 100 will be held directly facing and parallel to the at least one UV lamp 20. In one embodiment, wherein the device features a two-part hinged chamber, the at least one securing component 100 for holding the at least one item 22 may be positioned on the top wall adjacent to the opening. In an embodiment wherein the sterilization device 10 includes one UY lamp 20, the at least one securing component 100 for holding the at least one item may be positioned in the part of the chamber or connecting frame which holds the UV lamp 20. The position of the at least one securing component 100 for holding the at least one item 22 may be adjustable. Adjusting the position may facilitate optimal placement of different sizes and shapes of items 22 to be sterilized. This may be useful in a non-limiting example wherein the device is used to sterilize more than at least one item 22 or disconnected parts of the same item 22 at the same time. The position of the securing components 100 may be adjusted according to the position of the holding component 80, in which the item 22 is held. An additional at least one securing component 100 may be attached on the bottom face of the chamber. The at least one securing component 100 on the bottom face of the chamber may facilitate anchoring the at least one item and may prevent unwanted movement of the at least one item.

[0059] In an alternative non-limiting embodiment show schematically in Figure 9b, the at least one securing component 100 may be configured and positioned to hold the at least one item 22, so that the length of the item to be sterilized extends in a horizontal configuration 104. In one non-limiting example, the at least one securing component 100 may include at least two securing components 100, which may be attached to opposite facing side walls of the sterilization chamber. The at least one item 22 to be sterilized may be attached to the two securing components in any suitable way and at any suitable positions of the at least one item 22 so that its length extends horizontally along the width of the sterilization device. In such an embodiment, the at least one UV lamp 20 may be disposed so that its length extends horizontally and is attached adjacent to the bottom wall or the side wall or the top wall of the sterilization chamber 14. In a non-limiting example of such an embodiment, the at least one securing component 100 may include one securing component 100, such as a shelf or tray made from a UV transparent and resistant material, such as but not limited to quartz as shown schematically in Figure 9b. The at least one item 22 may be placed on the shelf 100 for sterilization. The shelf 100 may be removable.

[0060] The at least one item 22 may be held directly by at least one securing component 100 or may be held indirectly by the at least one securing component 100. Indirect holding may feature attaching or placing the at least one item 22 in a suitable UV transparent container 108.

[0061] The at least one item 22 to be sterilized may be placed in a container 108 as shown schematically in Figure 9c. The container 108 may facilitate retaining sterility of the sterilized item 22 when removing it from the sterilization device 10. The container 108 may be any suitable UV transparent container 108 sized to hold the at least one item 22. The container 108 may be disposable or reusable. The container 108 may be configured for holding one item 22 to be sterilized. More than one item 22 in the same container 108 may obstruct or hinder sterilization of all the surfaces of each item 22 in the container 108. In an embodiment in which more than one item 22 is placed in a container, the container 108 can be constructed with separators, such as compartments to separate each item of a plurality of items so that all the surfaces of each item can be exposed to the UV light. Non-limiting examples of suitable containers 108 include bags, trays and nets. The containers 108 may include corresponding attachment means 110 to attach to the respective at least one securing component 100 of the sterilization device. Corresponding attachment means 110 may include, but is not limited to corresponding hooks, links, ties, rail attachment means, press studs, ball and loop attachment means, clip connectors, clasps, pegs, magnets and ball and sockets. In some embodiments, the container does not include corresponding attachment means 110, such as but not limited to a container 108 for placement on a shelf in the sterilization chamber. The container 108 is configured to hold the at least one item 22 in an extended and unfolded configuration in order that the sterilizing UV light can reach all surfaces of the at least one item 22. In one embodiment, the container 108 may be designed such that the item 22 to be sterilized and held in the container 108 fits sufficiently tightly into the cavity of the container 108 so that it is anchored in a fully extended conformation. In an alternative non-limiting example, the container 108 may include ties or other suitable anchoring components, which are UV transparent and which are spaced apart to tie the at least one item and anchor it in an unfolded configuration within the container. The anchoring components are configured to ensure that the at least one item 22 maintains its unfolded conformation throughout the sterilization process. The anchoring components may be made from a UV transparent material. The at least one item 22 to be sterilized, such as, but not limited to a probe may be sufficiently rigid to maintain an extended unfolded configuration without the need for anchoring components. In one non-limiting example, wherein the at least one securing component 100 is a hook, the at least one item to be sterilized may be placed in a UV transparent bag 108. The bag 108 may include at least one ring component 110 on at least one of its extremities. The ring 110 may be attached to the hook 100 to hang the bag 108 and the item 22 held in the bag 108. In a further non-limiting example where the container 108 is a tray, the at least one item is placed on the tray in an extended unfolded conformation. The tray may be placed on a shelf of the sterilizing device. Alternatively, the tray may be slotted into grooves in the sterilization chamber, which are configured for receiving the tray. In an example wherein the at least one item 22 to be sterilized does not include a section which cannot be sterilized, the entire at least one item 22 may be held in the container 108. The container 108 may hold all the sections of the item 22 to be sterilized including a section 74 of the item, which is not to be sterilized and which is not to be held in the sterilization chamber 14. In one embodiment, a container 108 is configured to hold only the sections to be sterilized of an item to be sterilized. Such a container 108 may include an opening from which the section 74 of the item 22 which is not to be sterilized protrudes. The container 108 may be held and positioned in the sterilization device so that the sections of the item which are to be sterilized are in the sterilization cavity and the sections which are not to be sterilized are held external to the sterilization chamber. [0062] As shown schematically in Figure la, the sterilization device includes a component for opening 90 the sterilization device. The sterilization device 10 may include any suitable means for opening the sterilization chamber. The component for opening 90 may provide access to the cavity 12 of the sterilization chamber 14 for inserting the at least one item 22 to be sterilized in the sterilization chamber 14. Additionally, the opening component 90 may provide a user with access to any suitable part of the sterilization device for actions such as, but not limited to maintenance, replacement and cleaning. The opening can be closed during a sterilization cycle. The opening element 90 may include any suitable opening and closing mechanism. One non-limiting example of a suitable opening element 90 is a door. Figure 10a shows schematically a non-limiting example of a face 16 of the sterilization device 10 constructed as a door 90. Alternatively, part of a face 16 of the device may be constructed as a door. In one embodiment, the sterilization chamber may feature two parts of the chamber 82, 84 which are suitably attached to each other, such as, but not limited to hingedly attached 92 to provide a sterilization chamber 14 which opens to split the sterilization chamber and closes to reform the complete sterilization chamber. The two parts 82, 84 may be of equal size, such that the chamber 14 is opened along the midline 94 longitudinally. In one non-limiting example the sterilization chamber comprises a cylinder split longitudinally to two halves which are hingedly connected and which open to provide the opening of the device. Figure 10b shows a non-limiting example of the two part chamber. In one non-limiting example the two parts may be of unequal size as shown schematically in Figure 10c. The frame of the sterilization device may suitably hold the two parts of the chamber. In such an embodiment the respective part of the frame connected to each part 82, 84 of the sterilization chamber 14 may also be configured to open similarly to that described for the sterilization chamber in order for the sterilization chamber to adopt an open two part chamber as shown in Figure 10b and Figure 10c. Alternatively, the device may be held in the frame so that the frame does not open when the two parts 82, 84 of the sterilization chamber 14 are opened. Figure lOd shows schematically the non-limiting example of Figure 10b in a closed configuration.

[0063] As shown schematically in Figure la, the sterilizer 10 may include at least one sensor 120. The at least one sensor 120 may be any suitable sensor. The at least one sensor 120 may be for monitoring at least one of the sterilization cycles, the functioning of the sterilization device and the functioning of components in the sterilization device. The sterilizer may include a sensor for sensing when a sterilization cycle has been successfully completed. The sterilizer may be calibrated. Calibration may be done by the manufacturer. Calibration may be done with at least one indicator for indicating completion of surface sterilization, such as, but not limited to a biological indicator. The sensor may measure the UV light intensity. The sensor may include a photodiode. The information sensed by the sensor in conjunction with the calibration data of the device may be used to calculate the time for completion of sterilization. The device may include at least one temperature sensor, such as a thermometer 150, to measure and monitor the temperature and to avoid any unwanted heat effects on the at least one item being sterilized and components of the sterilizer. The sterilization device 10 may include a heat control to control the heat. The device may include an ozone sensor, to monitor the level of ozone in the sterilization chamber. The device may include a radiation sensor to monitor radiation intensity as described.

[0064] The sterilizer may include a power supply 122 and electrical connections for powering the sterilization device 10 and its components. The power supply 122 may be any suitable power supply that supplies power.

[0065] The at least one UV lamp 20 may be connected to the suitable power supply 122 and electronics for powering the at least one UV lamp 20. The power source 122 and electronics may be connected to the sterilizer 10 in any suitable way. In some embodiments, the power source 122 and electronics may be positioned external to the sterilization chamber 14. In some embodiments, the power source 122 and electronics may be positioned in any suitable part of the device 10. In one non- limiting example the power source 122 and electronics are contained in a suitable part of the frame of the sterilization device. In one non-limiting example the power source 122 and electronics are in the base 130 of the sterilization device. In one non-limiting example, the power source 122 and electronics may be in a unit on the top of the sterilization device. In an alternative non-limiting example, the power source 122 and electronics may be positioned at the side of the sterilization device 10.

[0066] The sterilizer device may include a control 132 as shown schematically in Figure 11. The device may include any suitable arrangement and order of the control components. The control 132 may include a switch 134 to start and stop the sterilization device. The control 132 may include a control for controlling the at least one UV lamp 136. The control may include a suitable keyboard 138. The controller may include power controlling means 140. The control may include a clock 142. The controller may include a timer 144. The control may include a means for controlling the time of a sterilization cycle. The control may include a UV pulse control 146. The controller may include a screen and a display 148. The control may include different programs of sterilization cycle 152. The programs may be provided as part of a menu. The programs may be preset and/or may be programmable.

[0067] The sterilizer of the present invention may be suitable for a variety of sterilization applications for sterilization of different items. The sterilizer may be used for sterilization of rigid items. The sterilizer may be used for sterilization of items with smooth surfaces. Non limiting examples of suitable uses include sterilization of medical probes, such as endo ultrasound medical probes, vaginal probes, rectal probes, medical aesthetic instruments, cosmetic instruments, gynecological instruments and dental instruments. The sterilizer may be used on flexible items, which can be contained in a rigid state in order that all the surfaces of the items are exposed to UV light. The sterilizer may find application for different end uses, such as but not limited to in medical and dental clinics, medical aesthetic clinics, cosmetic clinics, surgeries and hospital departments. The sterilizer may be used for sterilization of only one item per sterilization cycle. In some embodiments the sterilization device is configured for simultaneous sterilization of more than one item.

[0068] Sterilization System

[0069] The present invention provides a sterilization system 160 as shown schematically in Figure 12. The system 160 features a sterilization device 10 as described hereinabove and in Figures 1-11. The sterilization device may include a cavity 12 for placement of at least one item 22 for sterilization, at least one UV lamp 20 sufficiently powered for providing pulses of UV light to the at least one item 22 being sterilized in the sterilization device 10 and at least one reflector 30 for reflecting the UV light into the cavity 12 and onto the surfaces of the at least one item 22 being sterilized. The sterilization device 10 may be configured to hold an item 22 for sterilization, where the item includes a section for being held in the sterilization chamber for sterilization of that section and an additional section which is held external to the sterilization chamber while being connected to the section being held in the sterilization chamber. In one embodiment, the sterilization device 10 may be configured to hold an item 22 which does not include a non-disconnectable section for being held outside the sterilization chamber. In such an embodiment all the sections of the at least one item are positioned in the sterilization chamber and the sterilization chamber is adapted if needed to provide a closed sterilization chamber as described hereinabove. The system 160 further comprises a container 108 for holding the item 22 being sterilized as described hereinabove. The container 108 may also be for holding and retaining the sterilized item 22 after sterilization until use of the sterilized item. As previously described the container 108 is made from a suitable UV transparent material such as, but not limited to quartz, and polychlorotrifluoroethylene such as ACLAR ® . The item 22 to be sterilized may be held in the container 108, such that the item 22 adopts an unfolded extended configuration for efficient surface sterilization of all the surfaces on the item 22. The container 108 may be held in the device 10 by at least one securing component 100 similarly and as previously described for directly holding the at least one item 22 being sterilized. In one embodiment, the container may be held only by the holding component 80. The inside of the container 108 may hold all sections of the item 22 including sections that will be positioned outside the sterilization chamber during the sterilization process or may hold only sections that are accommodated within the cavity 12 of the sterilization chamber 14. In a non-limiting example wherein the at least one item 22 does not include a section which is not to be sterilized, the container 108 may hold all the sections of the at least one item.

[0070] Method of Sterilization

[0071] The present invention provides a method of sterilizing at least one item as shown schematically in the flow chart of Figure 13. The order of the steps is not meant to be limiting and any suitable order may be used. A sterilization device of the present invention is provided 200. The sterilization device may be suitably placed, which may be for proximity to the location of the end use of the items being sterilized in the device. The sterilization device is opened by any suitable opening mechanism 202. The item is placed in the device 204. In some embodiments, placing the item to be sterilized in the device may include placing the item to be sterilized in a container in a fully extended configuration 206. The container is configured to hold the item in an unfolded configuration, with the length of the item fully extended. In an example of a flexible item, which is to be sterilized, anchoring elements may be used to ensure the flexible item is fully extended and remains this way during sterilization. The item may be attached to the device 208. In an embodiment wherein the item to be sterilized is held in a container, the container may be attached to the device. An item in a container may be attached in any suitable way, so that the extended length of the container and item held within, is parallel to the length of the at least one UV lamp of the sterilization device and at a predetermined distance from the at least one UV lamp 210. In one embodiment the walls of the sterilization device are configured as reflectors to reflect the light from the UV lamp and optimize the light received on the surface of the at least one item for more uniform exposure and sterilization of the at least one item. The container with the stored item may be held by a securing component of the sterilization cavity of the sterilization device. Alternatively, the at least one item to be sterilized, which is not contained in a container may be attached directly to the securing component/s of the device in an extended unfolded configuration. The at least one item may be a probe which is rigid and which adopts an extended configuration. In a sterilization device wherein the UV lamp is attached to the device such that its length runs vertically from top to bottom of the sterilization device, the at least one item is attached to the sterilization cavity such that the length of the item runs vertically from top to bottom of the sterilization device. In a sterilization device wherein the UV lamp is attached such that its length runs horizontally along or adjacent the width of the at least one wall of the sterilization device, the at least one item is attached to the sterilization cavity such that the length of the item runs horizontally along the width of the sterilization cavity and the item lies parallel to the at least one UV lamp. In one embodiment, a section of the item to be sterilized, which is located at an extremity of the item is not sterilization resistant and the UV light can affect the functioning or material of the section. In such an embodiment, the item to be sterilized is attached in the sterilization chamber such that the section which is not to be exposed to the sterilization conditions such as pulses of UV light is held outside the sterilization chamber 212 whilst it is connected to the at least one section of the item held inside the cavity for sterilization. This may be accomplished by placing the section or a part of the section which is not for sterilization in a holding means, such as a cut out area, for example a recess of the frame, which is configured to hold a section of an item externally from the sterilization chamber. In an alternative embodiment, the item to be sterilized does not include a non-detachable section which needs to be held outside the sterilization chamber and the whole item may be attached or placed in a suitable way inside the sterilization chamber. In such an embodiment, the sterilization device may be adapted to provide a closed sterilization chamber during sterilization. Adapting may include plugging or closing any opening of the device with a closing element, the opening which may be configured to hold a non- detachable part of an item outside the sterilization chamber. In some embodiments, the distance between the item to be sterilized and the UV lamp can be changed. The distance can be changed by moving the UV lamp. The movement of the UV lamp may be automatic or manual. In an automatic mode, the distance may be changed according to the sterilization program chosen. The sterilization chamber is closed 214. The sterilization device is activated by switching it on. A sterilization cycle may be selected and selection may be according to the at least one item being sterilized 216. The sterilization cycle is started and the UV lamp provides pulses of UV light with properties according to the chosen program 218. The UV lamp provides UV light to the surfaces of the at least one item held in the cavity of the device to sterilize the surfaces of the sections of the at least one item held in the cavity. The UV pulses may provide energy on the surface of the at least one item of from about 0.5 J/cm 2 to about 5 J/cm 2 . The UV pulses may be provided for less than about 90 seconds. The UV light is reflected from the reflective surfaces off the sterilization chamber to provide UV light to the surfaces of the at least one item. In an embodiment, wherein the device includes reflector walls, the exposure of the at least one item to the UV light is optimized as in addition to the direct UV light from the lamp, UV light is also reflected by the reflector walls onto the surface of the at least one item. The sterilization cycle finishes 220. The time for duration of the cycle may be from a few seconds up to a few minutes. The time to complete sterilization can be changed according to the parameters used in the sterilization process, such as but not limited to the power of the UV lamp, the number of UV lamps, the number of pulses, the proximity of the item being sterilized to the UV lamp and the number of reflectors. The sterilization device may employ a sensor to determine that the sterilization cycle has been successfully completed. The sterilization device may indicate to a user that the item is sterile. The indicator may be any suitable indicator such as, but not limited to at least one of a light indicator, a message indicator and an audio signal. When a container is used, the container with the at least one sterile item may be left in the sterilizer until use. Alternatively, the container may be removed from the sterilizer and the at least one sterile item may be left in the container until use. The sterilization device is easy to use and can be mn by any suitable user.

[0072] Reference is made to the following examples, which together with the above descriptions illustrates the invention in a non-limiting fashion.

[0073] Example 1

[0074] An ultrasound technician places into a UV transparent bag a vaginal probe which has been used for an internal ultrasound examination on a patient. The probe is held tightly by the cavity in the bag which is shaped and sized to hold the probe. The technician opens a UV pulse sterilizer of the present invention. The technician opens it by pressing a button, which releases a lock. The device opens lengthways. The open configuration of the sterilizer features two similar walled halves of a cylinder, which are hinged together. The walls are configured to provide an internal cavity, which is completely surrounded by the walls when the device is closed. The sterilizer device includes one UV lamp attached to and spaced apart from a back wall to provide a gap between the UV lamp and the back wall, such that the length of the UV lamp extends vertically from the top to the bottom of the sterilization chamber. The top extremity of the bag includes a connector link, which corresponds to a hook positioned at an attachment point on the top wall of the frame of the sterilization chamber and adjacent to the opening of the sterilization device. The technician attaches the bag to the sterilization chamber by placing the loop of the bag over the hook. The technician inserts the probe such that the section at one extremity of the probe which includes an electric cable is placed in a groove of the frame of the sterilizer. The length of the bag and the probe inside extend vertically and are held parallel to the UV lamp. The technician closes the sterilization unit and the walls of the sterilization cavity completely surround the probe section for insertion into a patient and the handle section of the probe, both connected sections which are held in the sterilization cavity. The section of the probe which is held in the groove is located outside the sterilization cavity for substantially no exposure to the UV light. The technician selects a sterilization cycle for providing UV pulses for a set time to the probe. The technician presses the start button and the sterilization cycle is run. The sterilization device monitors the sterilization and indicates with a green light that sterilization has been completed. In this non-limiting example sterilization is completed within twenty seconds. The technician leaves the probe in the bag until her next examination.

[0075] Example 2

[0076] An instrument used in a medical aesthetic procedure is placed in a UV pulse sterilizer of the present invention as described herein. The whole instrument is positioned on a UV transparent shelf so that it is parallel to a UV lamp. The sterilization unit is closed and a sterilization cycle is selected for providing UV pulses for a set time to the instrument. The sterilization cycle is run. The sterilization device monitors the sterilization and indicates with a green light that sterilization has been completed. In this non-limiting example sterilization is completed within ninety seconds.

[0077] Example 3

[0078] A sterilization device of the present invention was used with a biological indicator Geobacillus stearothermophilus to assess optimal sterilization conditions. A UV Xenon lamp was configured vertically in the sterilization chamber, the lamp providing flashes of 1 Hz. Different distances of the indicator from the lamp were examined. It was found that with a 30 mm distance of the indicator from the lamp, using 5 flashes in 5 seconds, surface energy measured was 2.5 J/cm and a 6.4 log reduction of the spores was achieved. A 60 mm distance of the indicator from the lamp, using 18 flashes in 20 seconds, resulted in a measured surface energy of 1.4 J/cm and a 5.9 log reduction of the spores.

[0079] Example 4

[0080] Sterility level as a function of UV dose was evaluated using GbST in the sterilization device of the present invention. A UV Xenom lamp with a spiral UV lamp housing was used, emitting at a rate of 2 Hz. The indicator was placed 5.5 cm from the UV lamp for different time intervals, 10 seconds, 15 seconds, 45 seconds, 60 seconds and 90 seconds. A 6 log reduction in the spore population was obtained by irradiation for 45 seconds and up.

[0081] One skilled in the art can appreciate from the foregoing description that the broad systems, devices and techniques of the aspects of the present invention can be implemented in a variety of forms. Therefore, while the aspects of this invention have been described in connection with particular examples thereof, the true scope of the aspects of the invention should not be so limited since other modifications will become apparent to the skilled practitioner upon a study of the specification, and following claims.