Title:
USE OF GINKGOLIDE A IN THE TREATMENT OF AUTISM
Document Type and Number:
WIPO Patent Application WO/2021/082826
Kind Code:
A1
Abstract:
Use of ginkgolide A in the treatment of autism. Specifically, the present invention relates to use of ginkgolide A, a stereoisomer thereof, a crystal form thereof, a pharmaceutically acceptable salt thereof, a derivative thereof, an extract comprising ginkgolide A, or a combination thereof in the preparation of a pharmaceutical composition for the treatment of autism. The experiments have demonstrated that ginkgolide A can significantly alleviate the behavioral defects of autism, and ginkgolide A has the advantages of small dosage and high safety when treating autism, and is very suitable as a common medicine for the treatment of autism.
Inventors:
JING NAIHE (CN)
ZHANG KE (CN)
TANG KE (CN)
ZHANG KE (CN)
TANG KE (CN)
Application Number:
PCT/CN2020/117543
Publication Date:
May 06, 2021
Filing Date:
September 24, 2020
Export Citation:
Assignee:
CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE CHINESE ACAD OF SCIENCES (CN)
UNIV GUANGZHOU (CN)
UNIV GUANGZHOU (CN)
International Classes:
C07D493/22; A61K31/365; A61P25/00
Foreign References:
| CN1159022C | 2004-07-28 | |||
| US20120157445A1 | 2012-06-21 | |||
| CN100503613C | 2009-06-24 |
Other References:
ZHAO, JINGYI: "Formulation with Extracts from Ginkgo Biloba Leaves Using New Process Techniques", WORLD PHYTOMEDICINES, vol. 15, no. 4, 31 December 2000 (2000-12-31), CN, pages 174, XP009527836, ISSN: 1001-6856
SAMBROOK ET AL.: "molecular cloning: the conditions described in the laboratory manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
SAMBROOK ET AL.: "molecular cloning: the conditions described in the laboratory manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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