Title:
USE OF GOLD COMPOUND IN PREPARATION OF ANTIBACTERIAL AGENT
Document Type and Number:
WIPO Patent Application WO/2021/109292
Kind Code:
A1
Abstract:
Disclosed in the present invention is a use of a compound or a pharmaceutically acceptable salt thereof in preparation of an antibacterial agent. The compound has a structural formula shown as formula (I). The compound provided by the present invention can rapidly and effectively kill germs at a low concentration, thus achieving a good antibacterial effect.
Inventors:
YANG LIANG (CN)
LIU YUMEI (CN)
LIU YANG (CN)
HAN SHUHONG (CN)
LIU XIAOXUAN (CN)
LIU YUMEI (CN)
LIU YANG (CN)
HAN SHUHONG (CN)
LIU XIAOXUAN (CN)
Application Number:
PCT/CN2019/128968
Publication Date:
June 10, 2021
Filing Date:
December 27, 2019
Export Citation:
Assignee:
SOUTHERN UNIV OF SCIENCE AND TECHNOLOGY OF CHINA (CN)
International Classes:
C07F1/12; A61K31/66; A61P31/04
Foreign References:
| CN106573944A | 2017-04-19 |
Other References:
WU BIN, YANG XIAOJIAN, YAN MINGDI: "Synthesis and Structure–Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 62, no. 17, 12 September 2019 (2019-09-12), pages 7751 - 7768, XP055818172, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.9b00550
MARZO TIZIANO, CIRRI DAMIANO, POLLINI SIMONA, PRATO MARCO, FALLANI STEFANIA, CASSETTA MARIA IRIS, NOVELLI ANDREA, ROSSOLINI GIAN M: "Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure-Activity Relationships", CHEMMEDCHEM COMMUNICATIONS, WILEY-VCH, DE, vol. 13, no. 22, 20 November 2018 (2018-11-20), DE, pages 2448 - 2454, XP055818177, ISSN: 1860-7179, DOI: 10.1002/cmdc.201800498
VANESSA ALBERTINA AGERTT, LENICE LOREN�O MARQUES, PAULINE CORDENONSI BONEZ, TANISE VENDRUSCOLO DALMOLIN, GELSON NOE MANZONI DE OLI: "Evaluation of antimycobacterial activity of a sulphonamide derivative", TUBERCULOSIS, CHURCHILL LIVINGSTONE, vol. 93, no. 3, 1 May 2013 (2013-05-01), pages 318 - 321, XP055209268, ISSN: 14729792, DOI: 10.1016/j.tube.2013.02.003
MARZO TIZIANO, CIRRI DAMIANO, POLLINI SIMONA, PRATO MARCO, FALLANI STEFANIA, CASSETTA MARIA IRIS, NOVELLI ANDREA, ROSSOLINI GIAN M: "Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure-Activity Relationships", CHEMMEDCHEM COMMUNICATIONS, WILEY-VCH, DE, vol. 13, no. 22, 20 November 2018 (2018-11-20), DE, pages 2448 - 2454, XP055818177, ISSN: 1860-7179, DOI: 10.1002/cmdc.201800498
VANESSA ALBERTINA AGERTT, LENICE LOREN�O MARQUES, PAULINE CORDENONSI BONEZ, TANISE VENDRUSCOLO DALMOLIN, GELSON NOE MANZONI DE OLI: "Evaluation of antimycobacterial activity of a sulphonamide derivative", TUBERCULOSIS, CHURCHILL LIVINGSTONE, vol. 93, no. 3, 1 May 2013 (2013-05-01), pages 318 - 321, XP055209268, ISSN: 14729792, DOI: 10.1016/j.tube.2013.02.003
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
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