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Title:
USE OF HRPW-TYPE MULTI-MIMOTOPE LIGANDINS IN FOOD PRODUCTS, COSMETICS, HEALTH PRODUCTS OR PHARMACEUTICALS
Document Type and Number:
WIPO Patent Application WO/2022/142978
Kind Code:
A1
Abstract:
The present invention relates to the field of biomedicine. Provided is the use of HrpW-type multi-mimotope ligandins in food products, cosmetics, health products or pharmaceuticals. The HrpW-type multi-mimotope ligandins comprise HrpWPsda, HrpWPsst, HrpWPssc, HrpWPsce, HrpWPsss, HrpWPssp, HrpWPsca, HrpWPsco, HrpWPsav, HrpWPsto, HrpWEch, HrpWpst, etc. The HrpW-type multi-mimotope ligandins, as a class of ligandin molecules with a special structure rich in multiple epitopes (linear and conformational epitopes), can recognize, activate and bind to various types of animal membrane receptors, membrane proteins, information pathways and metabolic pathways across boundaries. The HrpW-type multi-mimotope ligandins are a class of special multi-mimotope ligandins with new functions, new action mechanisms and new application prospects.

Inventors:
WU BOJI (CN)
WU BAOZHEN (CN)
Application Number:
PCT/CN2021/134716
Publication Date:
July 07, 2022
Filing Date:
December 01, 2021
Export Citation:
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Assignee:
WU BOJI (CN)
WU BAOZHEN (CN)
KUNMING RUISIDE TECH CO LTD (CN)
International Classes:
A61P31/12; A61K38/16; A61P31/04; C07K1/14; C07K1/22; C07K19/00
Foreign References:
CN112773884A2021-05-11
CN101457228A2009-06-17
CN107002091A2017-08-01
CN1274259A2000-11-22
US20020083489A12002-06-27
Other References:
KIM, J.F. & BEER, S.V.: "HrpW of Erwinia amylovora, a New Harpin That Contains a Domain Homologous to Pectate Lyases of a Distinct Class", JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 180, no. 19, 1 October 1998 (1998-10-01), US , pages 5203 - 5210, XP002199591, ISSN: 0021-9193
ALEGRIA MARCOS C., DOCENA CASSIA, KHATER LETICIA, RAMOS CARLOS H. I., DA SILVA ANA C. R., FARAH CHUCK S.: "New Protein-Protein Interactions Identified for the Regulatory and Structural Components and Substrates of the Type III Secretion System of the Phytopathogen Xanthomonas axonopodis Pathovar citri", JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 186, no. 18, 15 September 2004 (2004-09-15), US , pages 6186 - 6197, XP055948883, ISSN: 0021-9193, DOI: 10.1128/JB.186.18.6186-6197.2004
Attorney, Agent or Firm:
CHENG DU HONG YI TIAN CHENG INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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