Title:
USE OF MALUS NIEDZWETSKYANA PRODUCT FOR INHIBITING BLOOD CLOT FORMAITON
Document Type and Number:
WIPO Patent Application WO/2021/098701
Kind Code:
A1
Abstract:
The present invention relates to the field of food and drugs, specifically to a use of a Malus niedzwetskyana product for inhibiting blood clot formation. The Malus niedzwetskyana product comprises a drug, a regular food product or a health food product, such as: fresh fruit, fruit juice, jam, freeze-dried powder, pressed candy, oral solution, capsules, etc. of Malus niedzwetskyana. Animal testing has shown that Malus niedzwetskyana products provide good blood clot formation inhibiting effects in both zebrafish and mice, are superior to regular apple products, and achieve a synergistic effect in combination with antithrombotic drugs.
Inventors:
SHEN YAN (CN)
ZHANG ZHENGFANG (CN)
WEN YI (CN)
HAN QUAN (CN)
HU LIU (CN)
ZHANG ZHENGFANG (CN)
WEN YI (CN)
HAN QUAN (CN)
HU LIU (CN)
Application Number:
PCT/CN2020/129650
Publication Date:
May 27, 2021
Filing Date:
November 18, 2020
Export Citation:
Assignee:
ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN)
International Classes:
A23L33/105; A61K31/05; A61P7/02; A61P9/10; A61K36/73
Foreign References:
| CN101837059A | 2010-09-22 | |||
| CN101692906A | 2010-04-14 | |||
| CN101554379A | 2009-10-14 | |||
| CN101554378A | 2009-10-14 | |||
| CN104115747A | 2014-10-29 |
Other References:
LU BINJIAN, YU KEKE; ZHANG YUGANG; DAI HONGYI; SUN XIAOHONG: "Analysis of Nutritional Components and Bioactive Substances in Red Flesh Apples", JOURNAL OF QINGDAO AGRICULTURAL UNIVERSITY (NATURAL SCIENCE), vol. 35, no. 1, 1 January 2018 (2018-01-01), pages 9 - 15, XP055821108, ISSN: 1674-148X, DOI: 10.3969/j.issn.1674-148X.2018.01.002
ZHANG XIANG, SUN XIAOHONG; BAI SUHUA; BO HUAIXIA; HOU HONGMIN; SUN XIN; ZHANG YUGANG: "Anthocyanin Content and Antioxidant Activity in Vitro of Red Flesh Apple Extracts", JOURNAL OF QINGDAO AGRICULTURAL UNIVERSITY (NATURAL SCIENCE), vol. 35, no. 3, 1 January 2018 (2018-01-01), pages 179 - 186, XP055821111, ISSN: 1674-148X, DOI: 10.3969/j.issn.1674-148X.2018.03.003
WANG XIAOQIAN, CUIYING LI, DONG LIANG, YANJUN ZOU, PENGMIN LI, FENGWANG MA: "Phenolic compounds and antioxidant activity in red-fleshed apples", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 18, 25 June 2014 (2014-06-25), NL, pages 1086 - 1094, XP055821113, ISSN: 1756-4646, DOI: 10.1016/j.jff.2014.06.013
QI NA, LEI JIA-LEI; DENG HONG: "Antioxidation and Anticancer Activity of Polyphenols from Red-flesh Apple of Hongxun No.1", ANHUI NONGYE KEXUE (JOURNAL OF ANHUI AGRICULTURAL SCIENCES), ANHUI SHENG NONGYE KEXUEYUAN, CN, vol. 47, no. 18, 1 January 2019 (2019-01-01), CN, pages 167 - 177, XP055821116, ISSN: 0517-6611, DOI: 10.3969/j.issn.0517-6611.2019.18.045
WRITING GROUP FOR THE PREVENTION AND CONTROL OF CHRONIC DISEASES IN MIDDLE-AGED AND ELDERLY PEOPLE: "Free Radical", PREVENTION AND TREATMENT OF CARDIOVASCULAR AND CEREBROVASCULAR DISEASES FOR MIDDLE-AGED AND OLDER PEOPLE, 31 August 2009 (2009-08-31), pages 20, XP009528694
ZHANG XIANG, SUN XIAOHONG; BAI SUHUA; BO HUAIXIA; HOU HONGMIN; SUN XIN; ZHANG YUGANG: "Anthocyanin Content and Antioxidant Activity in Vitro of Red Flesh Apple Extracts", JOURNAL OF QINGDAO AGRICULTURAL UNIVERSITY (NATURAL SCIENCE), vol. 35, no. 3, 1 January 2018 (2018-01-01), pages 179 - 186, XP055821111, ISSN: 1674-148X, DOI: 10.3969/j.issn.1674-148X.2018.03.003
WANG XIAOQIAN, CUIYING LI, DONG LIANG, YANJUN ZOU, PENGMIN LI, FENGWANG MA: "Phenolic compounds and antioxidant activity in red-fleshed apples", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 18, 25 June 2014 (2014-06-25), NL, pages 1086 - 1094, XP055821113, ISSN: 1756-4646, DOI: 10.1016/j.jff.2014.06.013
QI NA, LEI JIA-LEI; DENG HONG: "Antioxidation and Anticancer Activity of Polyphenols from Red-flesh Apple of Hongxun No.1", ANHUI NONGYE KEXUE (JOURNAL OF ANHUI AGRICULTURAL SCIENCES), ANHUI SHENG NONGYE KEXUEYUAN, CN, vol. 47, no. 18, 1 January 2019 (2019-01-01), CN, pages 167 - 177, XP055821116, ISSN: 0517-6611, DOI: 10.3969/j.issn.0517-6611.2019.18.045
WRITING GROUP FOR THE PREVENTION AND CONTROL OF CHRONIC DISEASES IN MIDDLE-AGED AND ELDERLY PEOPLE: "Free Radical", PREVENTION AND TREATMENT OF CARDIOVASCULAR AND CEREBROVASCULAR DISEASES FOR MIDDLE-AGED AND OLDER PEOPLE, 31 August 2009 (2009-08-31), pages 20, XP009528694
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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