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Title:
USES OF SUPER-OXYGENATED WATER AND GEL
Document Type and Number:
WIPO Patent Application WO/2021/212239
Kind Code:
A1
Abstract:
A super-oxygenated fluid selected from water, an aqueous solution and a gel is introduced to a living organism via any one of the following routes: transcutaneous, intradermal, subcutaneous, intraperitoneal and oral.

Inventors:
BEATTIE MICHAEL (CA)
Application Number:
PCT/CA2021/050569
Publication Date:
October 28, 2021
Filing Date:
April 26, 2021
Export Citation:
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Assignee:
GIS GAS INFUSION SYSTEMS INC (CA)
International Classes:
A61K33/00; A61K9/00; A61P17/02
Domestic Patent References:
WO2002060458A22002-08-08
WO2018078340A12018-05-03
WO2006133113A22006-12-14
WO2012140273A12012-10-18
Foreign References:
US10626036B12020-04-21
CA2299205A12000-09-09
CA2667614A12008-09-25
EP2149358A12010-02-03
US6139876A2000-10-31
US20080262413A12008-10-23
US6209855B12001-04-03
Other References:
READING ET AL.: "Oxygen absorption by skin exposed to oxygen supersaturated water", CAN. J. PHYSIOL. PHARMACOL., vol. 90, 2012, pages 515 - 524
RAZOOQI ET AL.: "Effect of oxygenated water alone or with vaccines and antibiotics on immune response against viral diseases and intestinal microflora community in broiler chickens", INDIAN JOURNAL OF FORENSIC MEDICINE & TOXICOLOGY, vol. 13, no. 4, 2019, pages 1263 - 1267
Attorney, Agent or Firm:
RIDOUT & MAYBEE LLP et al. (CA)
Download PDF:
Claims:
CLAIMS

1. Use of a super-oxygenated fluid selected from water, an aqueous solution and a gel, wherein the fluid is introduced to a living organism via any one of the following routes: transcutaneous, intradermal, subcutaneous, intraperitoneal and oral.

2. Use according to claim 1, wherein the level of dissolved oxygen is greater than 185% of saturation at normal total gas pressure.

3. According to another aspect of the invention, the fluid can be oxygenated using the device described in US 6209855.

4. According to another aspect, the fluid can be used in the healing of a wound, wound pCh can be monitored in real-time and the fluid can be introduced in response to wound site pCh.

Description:
USES OF SUPER-OXYGENATED WATER AND GEL

FIELD

This invention relates to the use of oxygen by biologicals, including humans.

BACKGROUND

It is well known that in living organisms, molecular oxygen has a key role in cellular health. A detailed description of the benefits of molecular oxygen is found in United States Provisional Patent Application Serial No. 63/014,764, filed April 24, 2020, incorporated herein by reference.

Hyperbaric chambers, which rely on the fact that oxygen can be absorbed through the skin, are commonly used as a means of maximizing the body’s access to oxygen. For example, hyperbaric chambers are commonly used by athletes to aid in recovery from high-exertion events.

However, use of a hyperbaric chamber for extended periods of time is both impractical and medically dangerous. Specifically, elevated blood-oxygen levels severely hamper the proper exchange of blood-oxygen with CO2 released from cells. This, in turn, releases a cascade of secondary issues mainly involving the Haldane and Bohr Effects.

SUMMARY

According to an aspect of the invention, a super-oxygenated fluid selected from water, an aqueous solution and a gel, is introduced to a living organism via any one of the following routes: transcutaneous, intradermal, subcutaneous, intraperitoneal and oral.

According to another aspect of the invention, in the fluid, the level of dissolved oxygen can be greater than 185% of saturation (i.e. 185% DO) at normal total gas pressure (TGP). According to another aspect of the invention, the fluid can be oxygenated using the device described in US 6,209,855.

According to another aspect, the fluid can be used in the healing of a wound, wound pC can be monitored in real-time and the fluid can be introduced in response to wound site pC .

DETAILED DESCRIPTION OF EMBODIMENTS OF THE INVENTION

One embodiment of the invention involves the transcutaneous introduction of the fluid to an organism for accelerated wound, bum healing and skin graft acceptance for small and large animals and humans and for the avoidance of wound ischemia.

Another embodiment of the invention is the use of the fluid for lavage purposes post surgery to increase healing and reduce pathogenic anaerobic bacteria populations.

Another embodiment involves the transdermal introduction of oxygen into an organism through the use of a pressurable cuff 20A having a chamber 22 into which the fluid is introduced through a fill and drain port 24, the chamber having a semi-permeable membrane 26 which is positioned against the skin 27 of the organism under pressure through the use of a pair of Velcro straps 28,30 and a pneumatic pressure chamber 32 which can be pressurized by a hand pump 34, all as shown in FIG. 1

Another embodiment of the invention is the introduction of the fluid via a neoprene udder bag 20B as shown in FIG. 2 for the treatment of bovine mastitis, the udder bag functioning in a manner similarly to that of the cuff but for the form factor, ie. having a chamber 36 for receiving fluid, a semi-permeable membrane 38, a pair of straps 40,42 and a pneumatic pressure chamber 44 which can be pressurized by a hand pump 46.

Another embodiment of the invention is the use of the fluid, in aqueous solution form, comprising vaccine in a drinking water supply for poultry or swine, as shown in FIG. 3.

More particularly, oxygenated water can be delivered from a tank 48 through a distribution manifold 49 and faucets 50 into a trough 52. Another embodiment of the invention is the use of the fluid in the form of an aqueous solution comprising vaccine in a tank containing live shrimp.

Another embodiment of the invention is the use of the fluid in the form of an aqueous solution comprising antibiotic in a drinking water supply for poultry, swine or cattle, for enhanced drug uptake.

Another embodiment of the invention is the use of the fluid in the form of an aqueous solution comprising antibiotic in a tank containing live shrimp for enhanced drug update.

Another embodiment of the invention is the introduction of the fluid into the header tank or well-feeder line in a milk cattle bam for the improvement of nutrient absorption, immune response and milk production.

Another embodiment of the invention is the introduction of the fluid in the form of water from a supply 54 into a bath or whirlpool 56, as shown in FIG. 4, for a diabetic to prevent ischemia.

Another embodiment of the invention is the introduction of the fluid in the form of water into a bath or whirlpool for athletic recovery.

Yet another embodiment of the invention is the introduction of the fluid via a bandage, as shown in FIG. 5. In this case, the bandage has an oxygenated gel 58 which can be held against the skin 59 by an adhesive strip 60.

Whereas specific embodiments are shown and described, it will be apparent that variations are possible. Without limitation in this regard, devices other than that shown in US 6209855 can be used to infuse the oxygen to the desired levels while maintaining total gas pressure. Accordingly the invention should be understood to be limited only by the accompanying claims, purposively construed.