Title:
UTILIZATION OF CILASTATIN IN INHIBITING RENAL DISORDER
Document Type and Number:
WIPO Patent Application WO/2019/208777
Kind Code:
A1
Abstract:
One of the problems to be solved by the present invention is to provide an inhibitor of renal disorder induced by an iodine contrast medium. In the present invention, use is made of cilastatin or a pharmaceutically acceptable salt thereof.
Inventors:
SAITO AKIHIKO (JP)
GOTO SAWAKO (JP)
HIRAYAMA YOSHIAKI (JP)
SEKINE SAKARI (JP)
GOTO SAWAKO (JP)
HIRAYAMA YOSHIAKI (JP)
SEKINE SAKARI (JP)
Application Number:
PCT/JP2019/017963
Publication Date:
October 31, 2019
Filing Date:
April 26, 2019
Export Citation:
Assignee:
UNIV NIIGATA (JP)
DENKA COMPANY LTD (JP)
DENKA COMPANY LTD (JP)
International Classes:
A61K31/198; A61P13/12; A61K49/04
Domestic Patent References:
| WO2015111666A1 | 2015-07-30 | |||
| WO2015111666A1 | 2015-07-30 |
Foreign References:
| KR20170086851A | 2017-07-27 | |||
| US20110165264A1 | 2011-07-07 | |||
| JP2003261459A | 2003-09-16 | |||
| US9216185B2 | 2015-12-22 |
Other References:
GUIDELINES ON THE USE OF IODINATED CONTRAST MEDIA IN PATIENTS WITH KIDNEY DISEASE 2012, JSN, JRS AND JCS JOINT WORKING GROUP, pages 50 - 79
MARZOLO ET AL., BIOLOGICAL RESEARCH, vol. 44, 2011, pages 89 - 105
CHRISTENSEN ET AL., NATURE REVIEWS MOLECULAR CELL BIOLOGY, vol. 3, 2002, pages 258 - 268
OYAMA ET AL., LABORATORY INVESTIGATION, vol. 85, 2005, pages 522 - 531
NORDBY ET AL., SCANNING MICROSC, vol. 4, 1990, pages 651 - 666
TANAKA ET AL., BMJ OPEN, vol. 4, 2014, pages e004407
MORIYAMA ET AL., AM JRESPIR CRIT CARE MED, vol. 176, 2007, pages 70 - 77
ZHANG ET AL., KIDNEY INT, vol. 73, 2008, pages 608 - 614
ORLANDO ET AL., PROC. NATL. ACAD. SCI. USA, vol. 89, 1992, pages 6698 - 6702
DE ET AL., DIABETES, vol. 66, 2017, pages 1391 - 1401
See also references of EP 3785711A4
MARZOLO ET AL., BIOLOGICAL RESEARCH, vol. 44, 2011, pages 89 - 105
CHRISTENSEN ET AL., NATURE REVIEWS MOLECULAR CELL BIOLOGY, vol. 3, 2002, pages 258 - 268
OYAMA ET AL., LABORATORY INVESTIGATION, vol. 85, 2005, pages 522 - 531
NORDBY ET AL., SCANNING MICROSC, vol. 4, 1990, pages 651 - 666
TANAKA ET AL., BMJ OPEN, vol. 4, 2014, pages e004407
MORIYAMA ET AL., AM JRESPIR CRIT CARE MED, vol. 176, 2007, pages 70 - 77
ZHANG ET AL., KIDNEY INT, vol. 73, 2008, pages 608 - 614
ORLANDO ET AL., PROC. NATL. ACAD. SCI. USA, vol. 89, 1992, pages 6698 - 6702
DE ET AL., DIABETES, vol. 66, 2017, pages 1391 - 1401
See also references of EP 3785711A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
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