VASOPRESSIN RECEPTOR ANTAGONIST

WIPO Patent Application WO/2019/082910

A1

Provided are: a V2 receptor antagonist which has high water solubility and which is particularly suitable for injections; and a medicine containing the V2 receptor antagonist or the like. The present invention is a compound represented by general formula (I) (all symbols in the formula are defined in the description), a pharmaceutically acceptable salt thereof, or a solvate thereof.

WO/2001/074796	SUCCINOYLAMINO HETEROCYCLES AS INHIBITORS OF A$g(b) PROTEIN PRODUCTION
JP2002517483	[Title of Invention] Neuropeptide Y5 Receptor Antagonist

IWASAKI YOICHI (JP)
OKADA NAOKI (JP)
ITOH NAOYA (JP)
UCHINO YUJIRO (JP)
NAGASAKA YOSUKE (JP)
MASAKI HIDEKAZU (JP)

PCT/JP2018/039430

May 02, 2019

October 24, 2018

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TOA EIYO LTD (JP)

C07D215/08; A61K31/395; A61K31/47; A61K31/55; A61K31/551; A61K31/5513; A61K31/5517; A61K31/553; A61K31/554; A61P1/16; A61P3/12; A61P5/10; A61P7/00; A61P7/10; A61P9/00; A61P9/04; A61P9/12; A61P13/12; A61P43/00; C07D215/22; C07D223/16; C07D225/06; C07D243/12; C07D243/14; C07D267/14; C07D281/10; C07D401/12; C07D403/10; C07D405/12; C07D409/12; C07D413/10; C07D471/04; C07D471/08; C07D487/04; C07D487/08; C07D498/04

WO2012059442A2

2012-05-10

JP2013505914A	2013-02-21
JP2009521397A	2009-06-04
CN102030709A	2011-04-27

MATSUHISA, AKIRA ET AL.: "Nonpeptide arginine vasopressin antagonists for both VIA and V2 receptors: synthesis and pharmacological properties of 4'-(1, 4, 5, 6- tetrahydroimidazo [4, 35-d][1]benzoazepine-6- carbonyl)benzanilide derivatives and 4'-(5, 6-dihydro-4H- thiazolo[5, 4-d][1]benzoazepine-6-carbonyl) benzanilide deriv", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 48, no. 1, 2000, pages 21 - 31

THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)

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