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Title:
WATER-DISPERSIBLE CANNABIDIOL PRODUCT AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/073019
Kind Code:
A1
Abstract:
Disclosed are a water-dispersible cannabidiol product and a preparation method therefor. The water-dispersible cannabidiol product comprises a product which can be prepared by means of the following method: adding an organic phase containing cannabidiol into a water phase for emulsification; after an organic solvent in an emulsion has been removed, adding glycosylase for a glycosylation treatment; and conducting drying to prepare the water-dispersible cannabidiol product. The prepared dispersible cannabidiol product can be quickly dispersed and dissolved in an aqueous solution. The product after the glycosylation treatment is a glucoside mixture in which cannabidiol is a parent nucleus structure and in which different sugar chain structures have been introduced to phenolic hydroxyl groups.

Inventors:
SONG YUNFEI (CN)
QIN BENJUN (CN)
XIE YONGFU (CN)
Application Number:
PCT/CN2020/074840
Publication Date:
April 22, 2021
Filing Date:
February 12, 2020
Export Citation:
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Assignee:
GUILIN LAYN NATURAL INGREDIENTS CORP (CN)
International Classes:
A23L33/105; A23L2/38; C12P19/18
Domestic Patent References:
WO2018176055A22018-09-27
Foreign References:
CN110693027A2020-01-17
CN110179862A2019-08-30
CN108642105A2018-10-12
CN108850558A2018-11-23
US5155219A1992-10-13
Other References:
ZHAO, QIANJING, CHENG YAO;WANG JIA;SUN XINXIAO;SHEN XIAOLIN: "Advances in the Use of Glycosyltransferases in Glycoside Synthesis", BEIJING HUAGONG DAXUE XUEBAO (ZIRAN KEXUE BAN) = BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY. JOURNAL (NATURAL SCIENCE EDITION), BEIJING HUAGONG DAXUE,, CN, vol. 45, no. 5, 31 October 2018 (2018-10-31), CN, pages 92 - 99, XP055803721, ISSN: 1671-4628
ZHU, BORU: "The Progress in the Study on the Property, Applications and Immobilization of Cyclodextrin Glycosyltransferase", AMINO ACIDS & BIOTIC RESOURCES, vol. 19, no. 1, 1 January 1997 (1997-01-01), pages 36 - 39, XP055803728, DOI: 10. 14188 /j . ajsh. 1997. 01. 010
ARAMSANGTIENCHAI P. ET AL.: "Synthesis of epicatechin glucosides by a β-cyclodextrin glycosyltransferase", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, vol. 73, no. 1-4, 30 July 2011 (2011-07-30), XP028296021, ISSN: 1381-1177, DOI: 10.1016/j.molcatb.2011.07.013
Attorney, Agent or Firm:
GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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