Title:
WATER SOLUBLE RAPAMYCIN DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2017/193562
Kind Code:
A1
Abstract:
A water soluble rapamycin derivative modified by glutathione and represented by formula I and a preparation method therefor. Definition to R1 and R2 is described in the specification. A compound represented by the formula I can be used for inducing immunosuppression and treating transplant rejection and diseases such as solid tumor.
Inventors:
WANG HAIBO (CN)
KUANG HONGFU (CN)
ZHANG WEI (CN)
CAI ZHENGJIANG (CN)
ZHU TIANMIN (CN)
ZHENG XIAOHE (CN)
WU ZHONGWEI (CN)
YANG ZHIQING (CN)
KUANG HONGFU (CN)
ZHANG WEI (CN)
CAI ZHENGJIANG (CN)
ZHU TIANMIN (CN)
ZHENG XIAOHE (CN)
WU ZHONGWEI (CN)
YANG ZHIQING (CN)
Application Number:
PCT/CN2016/105178
Publication Date:
November 16, 2017
Filing Date:
November 09, 2016
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07K5/037; A61K31/436; A61P35/00; A61P37/06
Foreign References:
| CN101123878A | 2008-02-13 | |||
| CN102911251A | 2013-02-06 | |||
| CN1823081A | 2006-08-23 | |||
| CN105461738A | 2016-04-06 | |||
| CN104689330A | 2015-06-10 | |||
| CN102040569A | 2011-05-04 | |||
| CN102316902A | 2012-01-11 |
Other References:
See also references of EP 3299381A4
Attorney, Agent or Firm:
BOSS&YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
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