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JPS5285159A |
Pregnanes and androstanes are described which essentially possess a 3.alpha.-hydroxy group, a S.alpha.-hydrogen atom or a 4,5- or 5,6-double bond, a 17.alpha.-hydrogen atom and an 11.beta.-aminoester group. Other optional substituents or...
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JPS5283540A |
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JPS5271459A |
A method for treating arthritis which comprises administering to a subject in need of such treatment an effective amount of a fusidic acid derivative selected from compounds of the formula I: I in which R1 stands for a straight or branch...
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JPS5265260A |
Novel steroids having the structure AND THE 1,2-DEHYDRO DERIVATIVES THEREOF, WHEREIN R1 is chlorine, fluorine, or hydroxy and R'1 is hydrogen or R1 and R'1 together are =O; R2 is hydrogen or halogen; R3 is hydrogen, methyl, or fluorine; ...
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JPS526987B2 |
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JPS5212159A |
Therapeutically useful 16-dehydro-androstane derivatives of the general formula: processes for their preparation and pharmaceutical compositions for the treatment of dermatological disorders, which contain as active ingredient at least o...
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JPS51138668A |
DELTA 16-21-HYDROXY-20-KETO STEROIDS OF THE PREGNANE SERIES HAVING AN OTHERWISE UNSUBSTITUTED D-ring and a 13-methyl or -ethyl group, and 21-ethers and -esters thereof, are produced by reaction of a corresponding D-ring saturated 17-keto...
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JPS51136664A |
Novel compounds of the formula useful as pharmaceutical compounds are disclosed. Processes are also disclosed for their preparation.
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JPS5132626B1 |
Cpds. of partial general formulae I - IV where R'=OH or Oacyl and R2 = H or R'+R2 together = O R3 = H, beta-OH, beta-Oacyl, beta-halogen or alpha-halogen R4 = H or R3+R4 together = O R5 = halogen, OH or Oacyl R6 = H or R5+R6 together = a...
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JPS5128630B1 |
DELTA13(17) fusidene-21-acid and DELTA13,(17),20,(21)fusidadiene-21-acid derivatives (I) and (II). where the stereochemistry at position 20 is not determined and X and Y are each or and R=alpha or beta-hydroxy group or a straight or bran...
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JPS5124511B2 |
A method of preparing the 3,16α, 17 ξ -trihydroxy-11β-alkoxy-estra-1,3,5 (10) -triene of general formula I: **(See formula)** in which X represents a methyl or ethyl radical; R represents hydrogen or an unsaturated hydrocarbon radical...
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JPS5123484B2 |
Process for converting secondary and tertiary acetylenic carbinols to the corresponding alpha,beta-unsaturated carbonyl compounds by rearranging the carbinol with (trilower alkyl-, tricycloalkyl-, triaryl- or triarylalkyl-siloxy) vanadiu...
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JPS5154543A |
The present invention relates to a series of new fusidic acid derivatives and salts or easily hydrolysable esters thereof, to the preparation of these compounds and to pharmaceutical compositions containing the compounds. The new compoun...
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JPS50142556A |
The present invention relates to novel 11-substituted steroids of the estrane series having the general formula IN WHICH R1 = a free, esterified or etherified hydroxyl group or halogen; R2 = an alkyl group with 1-4 C-atoms; R3 = 0 or ( a...
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JPS5032157A |
Steroids bearing the substituent -X-NR1R2 wherein -NR1R2 is a tritium of carbon-14 labeled amino or amino-acid group and -X- is -R3-, -OCOR3-, =N-O-R3- or -NHCOR3- wherein R3 is -(CH2)nCO- in which n is 0-4, are useful as diagnostic agents.
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JPS5024262A |
The invention relates to novel 7-substituted-steroids of the oestrane series of the general formula:
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JPS505711B1 |
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JPS504657B1 |
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JPS504659B1 |
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JPS5014669A |
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JPS504061A |
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JPS49132064A |
The present invention relates to new conjugates of glycine and taurine with compounds of the fusidic acid series according to formulae I and II below, to methods for the preparation of such compounds, and to pharmaceutical compositions t...
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JPS4994659A |
Topical anti-inflamatory 11-oxygenated pregneno[17,16 alpha -d]-1', 3'-oxathiolanes of the formula I wherein R1 and R2, can be the same or different and are a hydrogen atom, an alkyl, a cycloalkyl, a cycloalkyl containing hetero atoms, a...
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JPS4943958A |
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JPS495354B1 |
1336434 14,18-Epoxyethanoimino steroids J R GEIGY AG 23 Oct 1970 [24 Oct 1969 24 July 1970] 50425/70 Heading C2U The invention relates to compounds of formula wherein R 1 is H, C 1-8 alkyl or benzyl; R 2 is H 2 or oxo; R 3 is free or ket...
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JPS493984B1 |
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JPS4886854A |
1424212 Preparation of #16-21-acyloxy-20- keto-steroids SCHERING AG 12 Feb 1973 [11 Feb 1972] 6820/73 Heading C2U Steroids of the formula (wherein the dotted lines in the rings indicate the optional presence of #1-, #6- and #9(11)- doubl...
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JPS4822696B1 |
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JPS4828462A |
A process for converting 17 alpha -vinyl-17 beta -hydroxy steroids to 17-(2-haloethylidene)-steroids, known intermediates for antifungal and progestational agents, by treating the 17 alpha -vinyl-17 beta -hydroxy steroids with vanadium t...
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