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Title:
【発明の名称】ジアルキルジクロロシランを用いるパクリタキセルの半合成
Document Type and Number:
Japanese Patent JP2003502290
Kind Code:
A
Abstract:
A process for the synthesis of paclitaxel from 10-deacetylbaccatin-III which is protected at the 7-position with a dialkylalkoxysilyl protecting group having the formula -Si(R)2(OR').

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Inventors:
Persautam Bemischetti
Francis S. Gibson
John El Dillon Jr.
Application Number:
JP2000621359A
Publication Date:
January 21, 2003
Filing Date:
May 18, 2000
Export Citation:
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Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/337; A61P35/00; C07D305/14; C07F7/04; C07F7/18; (IPC1-7): C07D305/14; A61K31/337; A61P35/00; C07F7/04; C07F7/18
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)



 
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