Title:
【発明の名称】金属薬剤用大環状キレート剤
Document Type and Number:
Japanese Patent JP2003509434
Kind Code:
A
Abstract:
This invention relates to macrocyclic chelants comprised of one or two heteroatom-containing bridges, compositions containing them and their use in medicine, particularly in diagnostic imaging and radiotherapy. This invention relates especially to the use of metal chelates of the macrocyclic chelants as metallopharmaceuticals in Magnetic Resonance Imaging (MRI) and radiopharmaceuticals. This invention also relates to macrocyclic chelants as bifunctional chelating agents (BFC's) for the labeling of biologically active targeting molecules such as proteins, peptides, peptidomimetics, and non-peptide receptor ligands, with metal ions and radioisotopes.
More Like This:
Inventors:
Shang Ryu
Application Number:
JP2001523615A
Publication Date:
March 11, 2003
Filing Date:
September 07, 2000
Export Citation:
Assignee:
DuPont Pharmaceuticals Company
International Classes:
A61K47/48; A61K49/00; A61K51/00; A61K51/04; A61K51/08; C07F1/08; C07F5/00; C07F9/6584; C07F9/6587; (IPC1-7): C07F9/6587; A61K47/48; A61K49/00; A61K51/00
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)