Title:
生理活性なゲピロン代謝産物を使用することによって心理的疾患を治療する方法
Document Type and Number:
Japanese Patent JP2004500362
Kind Code:
A
Abstract:
Bioactive gepirone metabolites, such as 3-OH gepirone (4,4,-dimethyl-3-hydroxy-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione), and their pharmaceutically acceptable salts and hydrates, can be used to alleviate psychological disorders or the symptoms thereof. The use of these compounds provides advantages over other therapeutic azapirones as they possess superior bioavailability, faster onset of action, and more stable plasma levels when administered to a mammal.
Inventors:
Kramer, Stephen Jay
Fabre, Louis Ef
Rudiger, Edward H.
Jevich, Joseph Pee
Fabre, Louis Ef
Rudiger, Edward H.
Jevich, Joseph Pee
Application Number:
JP2001546426A
Publication Date:
January 08, 2004
Filing Date:
December 18, 2000
Export Citation:
Assignee:
Fabre-Cramer Pharmaceuticals, Inc.
Rudiger, Edward H.
Jevich, Joseph Pee
Rudiger, Edward H.
Jevich, Joseph Pee
International Classes:
A61K31/506; A61P25/22; A61P25/24; A61P25/28; A61P25/32; C07D401/12; (IPC1-7): A61K31/506; A61P25/22; A61P25/24; A61P25/28; A61P25/32; C07D401/12
Attorney, Agent or Firm:
Takehiko Suzue
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane