Title:
インドリノン化合物を用いてc-kitチロシン蛋白質キナーゼ機能を調節する方法
Document Type and Number:
Japanese Patent JP2004500363
Kind Code:
A
Abstract:
The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers characterized by over-activity or inappropriate activity c-kit kinase.
Inventors:
Ken Ripson
McMahon, Gerald
McMahon, Gerald
Application Number:
JP2001546428A
Publication Date:
January 08, 2004
Filing Date:
December 22, 2000
Export Citation:
Assignee:
SUGEN,INC.
International Classes:
C07D403/06; A61K31/00; A61K31/404; A61K31/405; A61P1/00; A61P3/04; A61P5/00; A61P11/00; A61P11/06; A61P15/00; A61P19/08; A61P25/00; A61P27/16; A61P35/00; A61P35/02; A61P37/08; A61P43/00; C07D209/34; C07D409/06; (IPC1-7): A61K31/404; A61P1/00; A61P3/04; A61P5/00; A61P11/00; A61P11/06; A61P15/00; A61P19/08; A61P25/00; A61P27/16; A61P35/00; A61P35/02; A61P37/08; A61P43/00; C07D209/34; C07D403/06; C07D409/06
Domestic Patent References:
| JP2002532492A | 2002-10-02 | |||
| JP2003514851A | 2003-04-22 |
Foreign References:
| WO1998007695A1 | 1998-02-26 | |||
| WO1998050356A1 | 1998-11-12 | |||
| WO1999061422A1 | 1999-12-02 | |||
| WO1999048868A2 | 1999-09-30 | |||
| WO1998045708A1 | 1998-10-15 |
Attorney, Agent or Firm:
Reiko Tanaka
Koji Morita
Koji Morita