Title:
キノリノン鏡像異性体による性的機能不全および心血管疾患の治療法
Document Type and Number:
Japanese Patent JP2005503995
Kind Code:
A
Abstract:
Methods for treating specific patient groups for sexual dysfunction are provided. The methods of the present invention comprise the utilization of enantiomers of flosequinan, and pharmaceutical compositions comprising flosequinan enantiomers, in patients who are free of cardiac disease, who have not been treated with a drug that causes hypotensive effects, and/or who have not been given organic nitrites or nitrates. Flosequinan enantiomers, and pharmaceutical compositions comprising flosequinan enantiomers are administered to patients intranasally, orally, topically, and/or through respiratory inhalation. Additionally, the present invention is directed to compositions and methods for treating cardiovascular disease. In a preferred embodiment, the present invention contemplates using the enantiomers of flosequinan (and formulations comprising flosequinan) in subjects not concurrently treated with nitrites or nitrates.
Inventors:
Cutler Neil Earl.
Shramek John
Shramek John
Application Number:
JP2002559037A
Publication Date:
February 10, 2005
Filing Date:
January 24, 2002
Export Citation:
Assignee:
R.T.Alamo Ventures Eye LRC
International Classes:
C07D215/36; A61K9/72; A61K31/47; A61P9/00; A61P15/00; A61P15/10; (IPC1-7): A61K31/47; A61K9/72; A61P9/00; A61P15/10
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Kazunori Hashimoto