Title:
HIVプロテアーゼ阻害剤、それらを含有する組成物、それらの薬学的使用およびそれらの合成用材料
Document Type and Number:
Japanese Patent JP2005508867
Kind Code:
A
Abstract:
Compounds of formula (I) where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. Theses compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
Inventors:
Canaan Cock, Stacy S
Alexander, Zares N
Barbian, Mark Earl
Gary Elle, Bolton
Boyer, Fredrick Yee, Junior
Burke, Benjamin Jay
Horror, Todd Pee
Jewell, Tanya M
Joshra, Vala Prasad Bencata Nagendra
Kukela, David Jay
Lynton, Maria A
Machak, Jeff Jay
Mitchell, Renato Jay, Junior
Murphy, Sheen Tea
Lake, Siegfried H
Scaridsky, Donald Jay
Tat Rock, John H
Bernie, Michael Dee
Scott Sea, Virgil
Weaver, Stephen Yee
Worland, Stephan Tea
Melnik, Michael
Alexander, Zares N
Barbian, Mark Earl
Gary Elle, Bolton
Boyer, Fredrick Yee, Junior
Burke, Benjamin Jay
Horror, Todd Pee
Jewell, Tanya M
Joshra, Vala Prasad Bencata Nagendra
Kukela, David Jay
Lynton, Maria A
Machak, Jeff Jay
Mitchell, Renato Jay, Junior
Murphy, Sheen Tea
Lake, Siegfried H
Scaridsky, Donald Jay
Tat Rock, John H
Bernie, Michael Dee
Scott Sea, Virgil
Weaver, Stephen Yee
Worland, Stephan Tea
Melnik, Michael
Application Number:
JP2003503613A
Publication Date:
April 07, 2005
Filing Date:
June 11, 2002
Export Citation:
Assignee:
Agron Pharmaceuticals Incorporated
International Classes:
A61K31/40; A61K31/401; A61K31/4025; A61K31/421; A61K31/422; A61K31/425; A61K31/426; A61K31/427; A61K31/428; A61K31/435; A61K31/439; A61K31/4439; A61K31/454; A61K31/4709; A61K31/472; A61K31/501; A61K31/5377; A61K31/541; C07D277/04; A61K38/04; A61K45/00; A61P31/00; A61P31/12; A61P31/18; A61P37/02; A61P43/00; C07D207/09; C07D207/16; C07D207/24; C07D209/52; C07D213/38; C07D217/26; C07D231/12; C07D263/04; C07D263/06; C07D277/00; C07D277/06; C07D277/20; C07D277/28; C07D277/32; C07D277/38; C07D277/60; C07D295/13; C07D307/52; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D417/14; C07D471/08; C07K5/04; (IPC1-7): C07D207/16; A61K31/40; A61K31/422; A61K31/426; A61K31/427; A61K31/4439; A61K31/501; A61P31/12; A61P31/18; A61P43/00; C07D263/06; C07D277/04; C07D277/06; C07D277/20; C07D277/32; C07D417/12
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Reiko Izumiya
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Reiko Izumiya