Title:
PPAR活性を調節する化合物、及び該化合物の製造方法
Document Type and Number:
Japanese Patent JP2005521741
Kind Code:
A
Abstract:
This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds of their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of suppressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.
Inventors:
Filsen, Gary Frederick
Trivedy, Bucharat Calidas
Gayor, Andrew George
Unungst, Paul Charles
Bratton, Larry Don
Outer batch, Bruce Jeffrey
Trivedy, Bucharat Calidas
Gayor, Andrew George
Unungst, Paul Charles
Bratton, Larry Don
Outer batch, Bruce Jeffrey
Application Number:
JP2003582115A
Publication Date:
July 21, 2005
Filing Date:
March 24, 2003
Export Citation:
Assignee:
Warner-Lambert Company Limited Liability Company
International Classes:
A61K31/19; A61K31/192; A61K31/353; A61K31/381; A61K31/404; A61K31/4168; A61K31/4178; A61K31/42; A61K31/422; A61K31/4245; A61K31/44; A61K31/4402; A61K31/445; A61K31/4525; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P35/00; A61P43/00; C07C27/02; C07C51/09; C07C59/135; C07C59/70; C07C59/72; C07C315/04; C07C317/22; C07C319/20; C07C323/19; C07C323/20; C07C323/21; C07D209/10; C07D211/14; C07D211/18; C07D213/20; C07D213/30; C07D213/32; C07D231/12; C07D233/68; C07D235/18; C07D261/08; C07D271/06; C07D271/10; C07D295/092; C07D307/79; C07D311/58; C07D333/54; C07D405/06; C07D405/10; C07D405/12; C07D413/04; C07D413/12; C07D521/00; (IPC1-7): C07C59/135; A61K31/192; A61K31/353; A61K31/381; A61K31/404; A61K31/4168; A61K31/4178; A61K31/42; A61K31/422; A61K31/4245; A61K31/44; A61K31/4402; A61K31/445; A61K31/4525; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P35/00; A61P43/00; C07C27/02; C07C51/09; C07C315/04; C07C317/22; C07C319/20; C07C323/20; C07C323/21; C07D209/10; C07D211/14; C07D211/18; C07D213/30; C07D213/32; C07D233/68; C07D261/08; C07D271/10; C07D311/58; C07D333/54; C07D405/06; C07D405/10; C07D413/04
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama