Title:
チュブリン阻害剤の合成に有用な中間体の合成方法
Document Type and Number:
Japanese Patent JP2006500407
Kind Code:
A
Abstract:
The invention is a process for the preparation of compounds of the Formula I: where R1, R2, R3, R4 and R5 are defined in the specification, which are intermediates useful for the preparation of tubulin inhibitors which are useful in the treatment of cancer.
Inventors:
Yang Jung Woo
Slini Vasle Megaty
Konstantin Grezos
John Thomas Kendall
Bogdan Kazimiels Wilk
Surairaja Padmanasan
Panoryl Labine Dranas
Slini Vasle Megaty
Konstantin Grezos
John Thomas Kendall
Bogdan Kazimiels Wilk
Surairaja Padmanasan
Panoryl Labine Dranas
Application Number:
JP2004537780A
Publication Date:
January 05, 2006
Filing Date:
September 12, 2003
Export Citation:
Assignee:
Wyeth Holdings Corporation
International Classes:
C07C269/06; C07C45/44; C07C45/58; C07C231/18; C07C237/22; C07C269/08; C07C271/22; C07C313/06; C07K5/02; A61K38/00; C07B57/00
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Tadayuki Motoyama
Kenji Tomita